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Showing content with the highest reputation on 07/23/2018 in all areas

  1. Hi Everybody First, I would like to thank everybody on this site for all the information, which I have found fantastic over the last couple of weeks of devouring this site in search of some relief. I am currently in the middle of my second cycle, the first happened 6 years ago (I had thought I was one of the lucky ones who would only ever have one cycle). Currently I live in Europe and have found getting oxygen for relief near impossible in my location. However, during my previous crisis, I used Oxygen and it was like a wonder drug. Clearly in most of the developed world (US/Europe/C
    2 points
  2. The new theory still needs to be tested ... but implies that cigarettes might create CH and happens when testosterone is low... (my understanding). The hypothesis theory will include several principles: (1) the need of double lifetime tobacco exposure, (2) that cadmium is possibly the primary agent in cigarette smoke that leads to hypothalamic‐pituitary‐gonadal axis toxicity promoting cluster headache, (3) that the estrogenization of the brain and its specific sexually dimorphic nuclei is necessary to develop cluster headache with tobacco exposure, and (4) that the chronic effects
    1 point
  3. I don't know what's new in terms of causation. Nothing that has made a difference in pharmaceutical treatments. (Some promising clinical trials, including one at Yale of psilocybin.) New in terms of "citizen science" treatment -- the D3 regimen (see ClusterBuster Files section of this board) has been very positive; maybe it's new that you can split your trex injections from an autoinjector (also in CB Files section, on page 2 I think, title is "Extending Imitrex"); and Batch strongly believes that allergies affect CH, so he recommends Benadryl 3x/day at 25mg and nighttime at 50mg. Razor pos
    1 point
  4. If you look at the figures, the difference between control and patients is at most about 10%. It's statistically significant, but impossible to say whether it's pathological. snp s don't always alter the function of a gene / protein in a significant way. I've attached the full PDF of the publication. Rainero_et_al-2010-Headache-_The_Journal_of_Head_and_Face_Pain.pdf
    1 point
  5. Though smoking may not make the CH condition worse, smoking cessation will bring a lot other benefits to body.
    1 point
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