a potential new option in General Board Posted April 26, 2011 yury, my daughter was once prescribed clonazepam for her CH, so i did some looking into it. i don't claim to be an expert, but here's what i found. in a couple of very small, quite old studies, clonazepam was considered an effective treatment for cluster headaches (in one case, combined with lithium). http://www.ncbi.nlm.nih.gov/pubmed/1104361 http://www.ncbi.nlm.nih.gov/pubmed/10498239 but today, from what i have read, it's only an "exceptional" treatment in limited circumstances, for example: http://www.ncbi.nlm.nih.gov/pubmed/18563291 it's more effective for trigeminal neuralgia. it's an anticonvulsant/sedative,anti-anxiety drug, so, yes, it might "calm you down." some people with CH have taken it for sleeping problems, but i've never seen anyone say it helped their CH. it's not listed at all in the european standards for treatment/"prevention" of CH, at least as i read those standards: http://www.guidelines.gov/content.aspx?id=10471 as mystina said, and as is reinforced in the wikipedia page she linked to, abruptly quitting clonazepam can lead to nasty withdrawal symptoms.