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Batch's whole document is here: https://www.vitamindwiki.com/tiki-download_wiki_attachment.php?attId=7708.  At the bottom of page 2 is the table showing the ingredients, which I can't/don't know how to insert here, but is a lot easier to read. 

Of course, you should read the whole document.  I'm going to quote some core things from pages 2, 5, and 6, but I'm not saying I'm not leaving out anything important!  These quoted sections do not include the "loading" process to quickly ramp up D levels, which is described beginning at the bottom of page 7.

Page 2: Anti-Inflammatory Regimen.  The suggested nutrients and their doses used in the Anti-Inflammatory Regimen for adults are shown in Table 1 and Figure 2 below.  Children with CH should receive a vitamin D3 dose of 50 IU per pound of body weight.  The other nutrients and supplements should be taken at RDA for the appropriate age group.

> Vitamin D3 (Cholecalciferol) 10,000 IU/day (Adjust as needed to keep serum 25(OH)D near 80 ng/mL)

> Omega 3 Fish Oil 1000 to 2400 mg/day (Minimum of EPA 360 mg/day, DHA 240 mg/day)

> Calcium * 220 to 500 mg/day

> Magnesium  400 - 800 mg/day (magnesium chloride, glycinate or oxide)

> Vitamin K2 (MK-4 & MK-7) MK-4 1000 mcg/day, MK-7 200 mcg/day (MK-7 preferred due to half-life)

> Vitamin A (Retinol) * 900 mcg (3,000 IU) for men, 700 mcg (2,333 IU) for women (Maximum Dose)

> Vitamin B 50 ** 3 month course, after that, the 7 B vitamins in the Mature Multi will be sufficient

> Zinc * 10 mg/day

> Boron * 1 mg/day minimum, 3 mg/day optimum

* Included in the Kirkland brand Mature Multi in sufficient quantity

** Vitamin B 50 is a single pill formulated with the seven B vitamins plus 400 mcg of folic acid.  Dr. Stasha Gominak, MD, a neurologist at ETMC, Tyler, TX, suggests a 3-month course of vitamin B 50 to address any deficiencies among the seven B vitamins.  The anti-inflammatory regimen can be used by itself or as an adjuvant therapy along with the Standards of Care recommended treatments for CH 

Page 5.  Order the following lab tests to establish a baseline before starting the anti-inflammatory regimen:

o 25-Hydroxyvitamin D3 [25(OH)D3].  CPT Code 82306.  Quest Diagnostics Test Name: 92888- QuestAssureD 25-OH Vitamin D (Total), LC/MS/MS.  95% of CHers with active bouts of cluster headache will have a 25(OH)D serum concentration ≤ 47 ng/mL, (117.2 nmol/L).  Any 25(OH)D serum concentration < 50 ng/mL, (125 nmol/L) is grounds for starting this regimen.

o Vitamin B12 (Cobalamin). CPT Code 82607

o Parathyroid Hormone (PTH) Intact and Total Calcium.  CPT codes 83970, 82310.  Establish baseline.

o CBC (w/ Differential and Platelets). CPT Code 85025. (Abs) Eos >350 indicates possible allergy

o Eosinophil Count, Nasal.  CPT Code 89190 o Lab results for Erythrocyte Sedimentation Rate (ESR) CPT Code 85652, C-Reactive Protein (CRP) CPT Code 86140 and plasma viscosity may prove useful if inflammation is suspected

Page 6. 50 mg/day (25 mg twice a day or 50 mg at bed time) Benadryl plus additional vitamin D3 up to 50,000 IU/day may be required to maintain a CH pain free response during periods of high pollen count resulting in an allergic reaction.  Caution patient that Benadryl (Diphenhydramine hydrochloride) can and will cause drowsiness and not to drive when taking it if at all possible.  Some CHers have reported that 12.5 mg Children’s Allergy Relief Liquid Benadryl taken twice a day is also very effective with less drowsiness.


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