They are all pretty vines with bell-shaped flowers and heart-shaped leaves. They are members of the family Convolvulaceae, and some of them have seeds that contain a tryptamine called lysergic acid amide or LSA. LSA seems to be an effective treatment for cluster headaches while usually having only a mild psychedelic effect – when it has any psychedelic effect at all. As with many sources of tryptamine, many report a feeling of mild to moderate nausea. For most, it is little problem, but it can be unpleasant.
The vines that make these seeds include the Rivea corymbosa (RC), Hawaiian baby woodrose (HBWR), and some strains of morning glory. Morning glory seeds have problems as they contain some unfriendly chemicals – teenagers who think they can get high from them generally get a lot more sick than high.
Clusterbusters have used the Rivea corymbosa and Hawaiian baby woodrose seeds successfully to treat cluster headaches.
The Rivea corymbosa and Hawaiian baby woodrose plants are not illegal to grow. It’s even legal to buy, sell and possess the seeds. It is LSA that is illegal, and it’s illegal to ingest the seeds or extract the LSA from them.
See WARNINGS! Read this first: Warnings
See Legal information here: Legal
RC and HBWR seeds are available though various Internet vendors and can be legally bought and owned – but only for gardening purposes. Both plants thrive in a semitropical environment and can be easily grown for their seeds in those climates. In the US, the growing area for RC includes Texas, Louisiana, Florida and Puerto Rico. For HBWR, the growing area is limited to Florida, Puerto Rico and Hawaii.
LSA seeds seem to have a limited shelf life. Keeping them cool, dry and away from light and air should help keep their potency. They can be frozen for longer storage.
The various natural sources of LSA may contain other related substances in the ergot family, and some of these are not so friendly. Many have a severe vasoconstrictive effect – narrowing the blood vessels and reducing blood flow, sometimes dangerously – that can cause serious, even fatal medical consequences. There is evidence these substances can trigger miscarriage. See WARNINGS! Read this first: Warnings
This vine, with large white bell-shaped flowers and heart-shaped leaves grows in Mexico and Central America, and is sometimes called Mexican morning glory or Christmas vine. The seeds are called ololiuqui, and they have been a favorite hallucinogen of the region for centuries. We call them RC seeds (we don’t know how to pronounce “ololiuqui”) and they are a useful source of lysergic acid amide.
The seeds, unfortunately, can be quite variable in their LSA content, and cautious clusterheads will work up slowly from a small number of the seeds, 8 or 10 at first, until there is a noticeable but mild effect. Many reports from those with CH over the years indicate that the number of seeds for effective treatments can be 40 or more. Seeds lose their potency over time, and some have little or no LSA to begin with. This may vary from batch to batch. Due to this variable potency each person must find a dose effective for them.
Some people experience little or no effect, some experience an odd drowsiness, others may have a significant or even powerful psychedelic experience from doses effective for cluster headaches.
The seeds should be crushed to a rough powder in some way: crushed in a mortar, ground in a pepper grinder or smashed between two spoons. The powder should then be soaked in a small amount of water for about an hour. This step is not to extract LSA from the seeds, but it is necessary to hydrolize the LSA molecules – the water soak adds hydroxyl ions to make the LSA available to the body.
Some strain the seed particles out of the liquid and drink it; others down the whole slurry, seeds and all at once. And quickly – the taste is horrible. A glass of water will be needed as a chaser. Citrus or cranberry juice is good to clear the nasty flavor.
The Hawaiian Baby Woodrose or HBWR for short, is also a flowering vine related to Rivea corymbosa and morning glory, and its seeds contain LSA. They are a popular ornamental and available for gardening purposes from many of the same suppliers of RC seeds.
HBWR seeds are a good bit larger and more potent than RC seeds. The beginning dose might be one or two seeds, with increases later, one seed at a time, if needed. As with LSA from RC and other sources, some may see little or no effect, some an odd drowsiness, at cluster-treatment doses. However, a significant or even powerful psychedelic experience is possible and caution is advised.
HBWR have an outer hull that contains some unfriendly chemicals. The idea is to pick the softer inner parts out of the tougher, outer hull. Dump the hulls. Soak the inner parts for an hour in water.
As with RC seeds, some strain the seed particles out, others down the whole slurry. Swallow quickly with water and juice chasers.
Morning glory seeds also contain LSA, but they can possibly be problematic, especially with commercially available seeds. The tiny seeds may contain some nasty chemicals along with the LSA, and extracting just the LSA requires a good knowledge of chemistry. Only certain strains of morning glory contain LSA, and commercial brands may be treated with pesticides. They are a favorite bad experiment among teenagers and abuse has drawn unwanted attention. Not recommended.
Common to dry areas in Mexico and the Midwest and Southwest of the U.S, sleepy grass is usually infected with a fungus that produces LSA. The formal name is Achnatherum robustum or Stipa robusta, and the fungus is of the genus Neotyphodium. It’s called sleepy grass because cattle and wildlife that eat it fall into a long, deep sleep. They wake up eventually and are fine, but will never eat sleepy grass again. There is little reported experience with sleepy grass, but there are reports of it being used recreationally.