I'm a female. I'm 25 and I've been suffering from clusters for as long as I can remember. Even as a child I would get them for a week at a time once a year. Now the pain is getting worse and they're getting longer in duration. Usually the cluster occurs each summer, but I have had some in the winter as well. I get one at least one a year. I'm currently in a cluster. The pain comes every other day, and last for about a 90 minutes. I can barely stand it. My eyelid droops, I get sick to my stomach, my eyes go crazy. Its like knives are stabbing me at the temples. Light hurts, sound hurts, smells hurts me. Every thing seems like a trigger to me; alcohol, smoke, caffeine, heat, stress, too much sleep, too little sleep, so many foods. I am on verapamil, topiramate, and then I begin predisone at 60mg and taper off when the cluster begins. I also have an oxygen tank. The oxygen doesn't seem to helping, maybe i'm doing it wrong. The pain is unbearable. I ended up in the ER yesterday and they gave me a benadryl cocktail, but by the time the doctor saw me, the cluster was already over. I guess I am looking for recommendations on anything. I never heard or considered drinking caffeine since it's such a trigger for me, but I'm willing to try drinking a caffeine shot next time. I'm willing to try anything. Maybe someone can offer me a suggestion about the oxygen as well. I use about 5 liters per minute when the pain starts for about 20 minutes. The pain just continues with such intensity that it feels useless. I see a neurologist at the mayo clinic and he has never said anything about injectable sumatriptan. However, this is something else I'd like to look into. I'm worried about side effects, but mostly I just want to find relief. I wonder why he never mentioned or recommended this to me in the past. Any help you can offer, will be much appreciated !!