I was on Lyrica the first year it came out. Went up to 600 mg. Still had major break through pain that put me on the floor. I do have a a level of tolerance, for instance, I walked around for 3 months with an infected appendacitcea and did not know it till I fell pain in my side driving.
Be careful with Lyrica, high doses may put leasions on your skin that look like cancer moles, mine disappeared when I stoped taking the med.