I had finished transitioning from episodic to chronic a few months before Emgality came out. Like EVERYTHING ELSE, it seems this "cure" works for some, and not for others, and like everything else (except oxygen for me), it's efficacy ebbs and flows. I have been on it for 11 months. It took a couple of months for Emgality to really take hold and then for about 6 months it was bliss, I could even have a couple of adult beverages, with just the occasional minor twinge in the last couple of days before re-dosing. Then, for a couple of months, I needed to be very careful with adult beverages, which is fine if its the only problem. But in the past 10 days, I have had 3 random headaches mid-day, but fortunately short ones with far less than "grand mal" pain levels. And way better than 20 headaches a month, which was what was happening before I went on Emgality. Hopefully this is just a temporary "ebbing", and it will return to "flowing" in a month or two.