I'm not clear on whether Gamma Core has worked for me. I've used it for almost a year along with Verapamil and Ajovy. Not sure if one of those, or the combination, has helped reduce my CHs. I was getting CHs chronically for about a year (before that, for a few months every Spring and Fall). But since I started the combo, I only get them 1 week out of the month. I'm afraid to stop Gamma Core though...don't want to mess with what is working. I believe Gamma Core has helped with calming my ADHD/Autistic brain a little bit (but not enough to make the price-tag worth it, though).