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Question about extended cycle duration after microdosing – anyone experienced similar?


Mike83
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Hello everyone,

 

I’m reaching out because I’m going through a very difficult time with my current cluster cycle, and I would really appreciate your insights or similar experiences.

 

I’ve been diagnosed with episodic cluster headaches for several years, and my cycles usually last around 3 to 4 months. This current cycle started on November 23, 2024, and now, in mid-June 2025, it’s still not over – which is the longest I’ve ever experienced.

 

 

Here’s some background:

 

 

  • I’ve been taking Verapamil regularly, most recently 240 mg × 3/day since June 7, 2025.
  • Before that, I was on 180 mg × 3/day, and at times I even lowered the dose during the cycle when symptoms improved.
  • During this cycle, I also started microdosing with psilocybin (approx. every 2–3 days) for several weeks – not busting, just very low doses.
  • I noticed that after starting the microdosing, the cycle didn’t improve, and possibly even worsened or extended.
  • I’m still using oxygen as an abortive (which usually works quickly), and I’ve also tried adjusting my diet, sleep, and supplements (D3 regimen, magnesium, etc.).

 

 

 

My question is:

 

 

Has anyone here experienced a significant extension of their cycle (past 6 months) after starting microdosing?

Could it be that the low doses kept the hypothalamus “awake” and prolonged the cycle?

 

I’m not sure if this is just a coincidence, or if the microdosing actually interfered. I’m now afraid that this may have caused a switch toward a more chronic pattern.

 

Any feedback, personal stories, or insights from others who went through something similar would mean a lot to me.

 

Thank you for your time and support,

Mike

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