Oxygen not effective and cycle changing? in General Board Posted 12 hours ago I'm sorry . . . I don't have anything more to suggest. If the liometacen/indomethacin is actually working, then it's possible (I imagine) that you might have a condition that has symptoms like cluster headache but is not the same, called a hemicrania. There are several types of that condition, most commonly hemicrania continua and paroxysmal hemicrania, and they can be either episodic or chronic. https://my.clevelandclinic.org/health/diseases/21538-hemicrania-continua#:~:text=Hemicrania continua and paroxysmal hemicrania both affect one side of,hemicrania causes repeated%2C sudden headaches. People with hemicranias generally do not get results from triptans, as it seems you don't, and they also generally do not get results from oxygen, which seems like it might also be true for you. They do get results from indomethacin, but it is administered in the form of a pill every day (multiple times a day) as a way to prevent attacks, and not, as you are using it, as an injection to stop an attack. Maybe you have also tried this. Usually the daily pills are taken with something to protect the stomach lining and digestive system. (I see you were here some years ago asking about busting. If that also didn't work for you, it would be a further indicator that you might have a hemicrania, since generally busting has little effect on hemicranias.) We can hope that when your O2 system is sorted out, you will start getting results from that and things will be much better. But, if you haven't done it already, I would look into the possibility of a hemicrania treated with indomethacin. Like I say, I'm very sorry for what you are experiencing, and very sorry that I haven't been able to be more helpful to you.