I need something fast, New user in General Board Posted August 2, 2011 Good for you, Christina! If I'm remembering right, sumatriptan is Imitrex. I'm a little out of my depth here, but I'll take a shot at an answer and let smarter people correct me if necessary. Yes, it will interfere with busting -- you're supposed to detox from meds like this for five days before busting. Is it injectable, or pill form? I think it's widely believed here that the pill form is not very effective. I guess that it would better for you not to use it if your seeds will be there in less than five days. If you don't mind, please tell us exactly what you're taking with the vitamins. Not everyone does this "right." You will want to move ahead with the oxygen, too. While busting works, it almost never works instantly, so you'll want to take several seed doses spaced five days apart. It's likely that you'll still get some headaches during that time -- in fact, what are called "post-dose hits" can be pretty severe (usually only once or twice). They're viewed here as a sign that you are shaking things up after a dose: often they also come at different times than your normal headaches. I'm hoping that the vitamin protocol might help you, but being able to abort attacks with oxygen helps you stay "detoxed" from things that block busting. I have some other thoughts, but gotta run right now. Again, congratulations on taking charge of this tough situation.