Dan_

The following study found that threshold doses of LSD (20ug) had a comparable analgesic effect on healthy participants as 15-20mg morphine. https://journals.sagepub.com/doi/full/10.1177/0269881120940937

So great to read about your success @AndiD! Wondering if it was tricky to get the oxygen suppliers to let you keep a couple bottles in storage when you're out of cycle? I'm London based and my supplier is Air Liquide, not really sure what to do about it when my cycle is up, would assume they'd be chasing me for them back after a while, but I wouldn't mind keeping one back just in case. Best of luck staying on top of it!

I know it's been mentioned above, but anyone considering quercetin - it's doubly important to speak with your doc if you're on verapamil. Below is from WebMD: Medications changed by the liver (Cytochrome P450 2C8 (CYP2C8) substrates) interacts with QUERCETIN Some medications are changed and broken down by the liver. Quercetin might decrease how quickly the liver breaks down some medications. Taking quercetin along with these medications that are changed by the liver might increase the effects and side effects of your medication. Before taking quercetin talk to your healthcare provider if you take any medications that are changed by the liver.<br><nb>Some medications that are changed by the liver include paclitaxel (Taxol), rosiglitazone (Avandia), amiodarone (Cordarone), docetaxel (Taxotere), repaglinide (Prandin), verapamil (Calan, Isoptin, Verelan), and others.

Hi guys, Two years ago I experienced my first cycle of CHs. The cycle lasted around 8-10 weeks, typically involving 3-5 headaches a day. On only one occasion did I experience an attack during the night (fortunately) which I remember being the most excruciating attack. I began to take a nasal spray of sumatriptan which offered partial relief, and around 8 weeks into the cycle I managed to procure some LSD, and began to experiment with the dosage. Shortly afterwards, my cycle appeared to fade away, although I'm not sure if it came to a natural end or if the LSD aborted it. Two years have passed without any symptoms, until this week. Two nights ago, I woke up in familiar and excruciating pain - the attack lasted around an hour and I was able to sleep again after. Tonight, I've been woken up again around the same time - this attack has been more intense. Am I right in assuming this is the start of a new cycle? So far I've only experienced these two attacks, both during the night, both very similar. I know episodes can be unpredictable, but I've been thrown off by the fact that it's only been one attack per night (as opposed to my previous cycle of 3-5 per day, with only one isolated attack in the night). Any insight from longer term sufferers would be appreciated. Solidarity with all of your poor souls. Dan