D3 regimen and Calcium blockers?

[Nikkk]

Hi again everyone,

sorry if i'm over sharing on here lately, i'm just getting out of a cycle after having been pain free for years and so i'm going again down the research rabbit hole..

I personally respond generally really well to mushrooms busting and D3 regimen seems to help too;

However due to high blood pressure i'm taking alpha and calcium blockers daily for 2yrs now, Isoptin retard 120mg, and losartan 50mg. 

My question is: can it cause issues one way or the other to use calcium blockers while doing the D3 regimen?

When addressing it to my doctor, he was just surprised by the amounts of supplements but he said that it's all green light by him, and that the calcium blockers aren't an issue there.

Thanks in advance,

<3

[CHfather]

There was a time when Batch suggested that people should take the calcium in the D3 regimen as far apart as possible from any calcium channel blocker meds.   I haven't seen that lately in his guidance.  (I think it's also true that in the early days there was a separate calcium pill that was part of the regimen, but now it's just what's included in the multivitamin, I think.)

[Nikkk]

@CHfather thank you for your response;

If I understand correctly you mean that if I take my calcium at 8am I should take the calcium blocker at 20pm?

[CHfather]

That seems right. As I say, this is just what I remember.  Looking back, I see this post from a well-informed member in 2015: "People taking verapamil (calcium channel blocker), for instance, do not necessarily need to take calcium supplements as they do not play well together.  If you do take both, then you need to take them far enough apart daily so that they do not interfere with each other."

Maybe @Craigo can comment.

[Nikkk]

@CHfather thank you!

Ill try to get some bloodwork done soon to see where i'm at. I was just surprised that my doctor seemed to not see any issues here though.

[Craigo]

Thanks CHfather – I don’t recall Batch’s earlier advice either, likely before my time.

We’re talking roughly 200–500mg calcium in a multi vitamin and most probably consume at least that daily through a standard diet. Check out this ask the Doctor post from Havard, although the patient was taking a different class of calcium channel blocker I suspect the answer would be the same.

While high doses of intravenous calcium are sometimes used to reverse an overdose of a calcium-channel blocker, the 600 milligrams of calcium in your daily supplement isn't enough to interfere with the drug's ability to lower blood pressure. In fact, oral calcium supplementation has been shown to lower blood pressure slightly in some people. So you can continue to take both without risking your bones or raising your blood pressure.

https://www.health.harvard.edu/blood-pressure/do-calcium-supplements-interfere-with-calcium-channel-blockers

As for vitamin D3, this study by Holick and colleagues looked at supplementation with 10,000iu D3 (amongst other doses) and found no change in serum calcium (albeit an increase in 25(OH)D and decrease in PTH). You could see an increase in calcium labs maintaining 80-120ng/mL however if maintained within normal reference my understanding is that you are good.

https://www.nature.com/articles/s41598-019-53864-1

You could jump on one of the Facebook or Reddit groups and ask the question there, I know a couple of chronic warriors that take both verapamil and the regimen together and are doing well. One comment about verapamil that stuck with me was that many warriors find the immediate release vs the sustained release works better for CH prophylaxis - why I am not sure but thought to add.

Happy holidays all.

[Nikkk]

@Craigo thank you!

this is reassuring news:)

And yes i'm taking quite small dose of calcium blockers anyways, for the blood pressure, which indeed keeping my blood pressure in check has shown to work well as prophylactic measure.

I'm currently (hopefully) on the verge of successfully bust a surprise cycle triggered by weaning off steroids that were prescribed for a pneumonia.. it has been messy since it was a surprise cycle I somehow panicked and started using sumatriptan spray to abort and I quickly realized that it made things worse so I dropped and went back to my dear fungi  

But since it has been such a roller coaster I started to dive back in the CH treatments and research rabbit hole.. and wanted to make sure i'm not doing anything stupid again out of panic!

Thank you again and happy holidays, and as we say in Iceland: Happy new year and thank you for the old one!

<3

[Craigo]

36 minutes ago, Nikkk said:

Thank you again and happy holidays, and as we say in Iceland: Happy new year and thank you for the old one!

 

Do you guys say this as you slurp another piece of fermented shark from the tin? Hehe. I really love that saying though, I will remember that!

Sorry to hear about your bout with pneumonia, glad you are on the mend from that - hopefully the steroids and I suspect antibiotics didn't mess you around too much. A couple of years ago I had a real bad run with a recurrent bacterial infection that used 5 rounds of antibiotics before my doctor presented a biologic which I had said absolutely not in a million years - saw a functional doc, got it under control but low and behold that was the one year I fell from cluster free remission whilst maintaining the target vitamin D3 range - opened my eyes to a few different topics including microbiome - sorry to say I don't know that the fermented shark packs a probiotic punch like kim chi though. 

You also mentioned in another post about foraging up there in Iceland for medicine, I suspect your varieties would be quite different to what's found in more warmer climates. It's the same in New Zealand, we have mystical magical varieties down under, one example being Psilocybe weraroa, they look like little blue testicles and pack a heck of a punch. 

Happy to see you here on the forums - I recently landed here earlier in the year, good bunch of folk here and we all seem to love cats. I feel like this is the more appropriate place to share recent research. 

So... I sign off by saying Happy new year and thank-you for the old one!

[Nikkk]

@Craigo thank you for the laughs:) I can definitely use those atm!

I don't touch hákarl ever tbh! it stinks more than it taste but unless it would abort CH I don't think I would eat it.

And yeah somehow CH have a sneaky way of teaching you about the fragile balance within our bodies hey.

Ok now I thought my mycology knowledge was rather advanced but I've never seen that NZ mushroom before! How funky! tbf i'm not too educated on non western fungi except for a few celebrities ofc. Here I pick mainly psilocybe semilanceata, it is potent indeed and quite consistent which is an advantage but definitely not as exotic as your alien testicles:)

cheers mate, hear you next year!