A possible new treatment principle for migraine

[cluster]

Jes Olesen: 5-Hydroxyptryptamine 1F (5-HT1F) receptor agonism. A possible new treatment principle for acute migraine attacks

http://cep.sagepub.com/cgi/content/long/30/10/1157

[Psiloscribe]

Thanks for this. Very interesting stuff.

Bob

[1961mom]

After CGRP antagonists, 5-HT1F agonists are the second class of substance to prove that migraine attacks can be treated with a drug that has no vascular activity.

This is the line I found to be so interesting....I have often wondered if the "body" doesn't throw in the vasodihalation as sort of an after thought or a response to what it perceives "must be occurring" when the pain center receives the pain messages.  Which I have read, has been proven in CH.  Pain first, vasodilation second.

Very interesting and thanks for posting cluster