cluster Posted September 20, 2010 Share Posted September 20, 2010 Jes Olesen: 5-Hydroxyptryptamine 1F (5-HT1F) receptor agonism. A possible new treatment principle for acute migraine attacks http://cep.sagepub.com/cgi/content/long/30/10/1157 Quote Link to comment Share on other sites More sharing options...
Psiloscribe Posted September 20, 2010 Share Posted September 20, 2010 Thanks for this. Very interesting stuff. Bob Quote Link to comment Share on other sites More sharing options...
1961mom Posted October 19, 2010 Share Posted October 19, 2010 After CGRP antagonists, 5-HT1F agonists are the second class of substance to prove that migraine attacks can be treated with a drug that has no vascular activity. This is the line I found to be so interesting....I have often wondered if the "body" doesn't throw in the vasodihalation as sort of an after thought or a response to what it perceives "must be occurring" when the pain center receives the pain messages. Which I have read, has been proven in CH. Pain first, vasodilation second. Very interesting and thanks for posting cluster Quote Link to comment Share on other sites More sharing options...
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