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"Cluster headache is a good case in point," he said. "Cluster headache is widely regarded as the most severe pain a human can experience — that's not hyperbole. It has a population prevalence that's approximately the same as multiple sclerosis."

Over the past decade, Shapiro said, NIH has directed $1.872 billion to multiple sclerosis research, which he said is warranted. By contrast, less than $2 million has gone to cluster headaches over the last 25 years. "It's completely invisible," he said.

Source: http://www.usatoday.com/story/news/nation/2013/05/16/researcher-unlocking-mysteries-migraines/2165363/

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