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D3 loading Schedule by Batch
Start by taking the basic regimen at 10,000 IU/day vitamin D3 on the first day. If there are no reactions (rare) to any of the supplement proceed with either of the two following accelerated vitamin D3 loading schedule. Be sure to take the rest of the anti-inflammatory regimen each day during this schedule.
Two-Week Vitamin D3 Loading Schedule
Week 1. 50,000 IU/day vitamin D3 for one week. Take all the other supplements.
Week 2. 40,000 IU/day vitamin D3 for six (6) days then drop the vitamin D3 dose to 10,000 IU/day on the 7th day. This will be the normal maintenance dose of vitamin D3. Take all the other supplements and cofactors daily.
Four-Week Vitamin D3 Loading Schedule
Week 1. 20,000 IU/day vitamin D3 plus one (1) loading dose of 50,000 IU/week vitamin D3
Week 2. 20,000 IU/day vitamin D3 plus one (1) loading dose of 50,000 IU/week vitamin D3
Week 3. 15,000 IU/day vitamin D3 and no loading dose
Week 4. 15,000 IU/day vitamin D3 and no loading dose
Take all the other supplements and cofactors daily. At the end of the 4th week, drop the vitamin D3 dose to 10,000 IU/day
plus the other supplements and cofactors.
These two vitamin D3 loading schedules are safe, equally effective and should result in a rapid 25(OH)D response to
therapeutic concentrations near 80 ng/mL with a significant reduction in the frequency, severity and duration of CH faster
than at the maintenance dose 10,000 IU/day vitamin D3.
The target serum concentration for 25(OH)D is 80 ng/mL so the total loading dose can be adjusted at the rate of 100,000
IU vitamin D3 per 10 ng/mL of 25(OH)D response. Vitamin D3 is lipophilic so adjustments can also be made for BMI.
Accordingly, if the BMI is <18.5, subtract 100,000 IU from the total loading dose. If the BMI is 25, add 100,000 to the
total loading dose.