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    • Do not use tryptamines if you are pregnant; they can cause miscarriage.
    • Do not use tryptamines if you suffer from or are prone to mental illness.
    • Tryptamines may interact with other medications.
    • Tryptamines have physiological effects.

    People diagnosed in the past or present with a psychotic disorder, or people with biological parents or siblings diagnosed with a psychotic disorder should not take tryptamines, including LSD, psilocybin, DMT and LSA. Psychotic disorders include schizophrenia, delusional disorder, affective (mood-related) psychosis and others. Tryptamines may exacerbate symptoms of psychosis or trigger psychosis in people who were psychotic in the past, or with immediate family members who were or are psychotic.

    Taking tryptamines during or immediately after a period of emotional upheaval, such as a relationship breakup the death of a loved one, may intensify negative emotions, even to a proportion that feels “out of control.”

    Tryptamines should only be taken when one feels confident and secure in his or her ability to handle a psychedelic experience and is confident in the stability of one’s mind set.

    Tryptamines should be taken only in a place where one feels secure and with people they can trust.

    Tryptamines and some of the chemicals found in natural substances containing tryptamines can cause miscarriage. Do not take tryptamines if you are pregnant or think you might be pregnant.

    Use of some tryptamines is known to increase heart rate and blood pressure, so consult with your doctor if you suffer any conditions that would be negatively affected by this.

    Reynaud’s syndrome (cold-triggered reduction or loss of circulation in fingers and toes) will be made worse by taking a vasoconstrictor, and tryptamines are vasoconstrictors.

    People taking lithium, whether for preventing cluster headaches or for some other reason, should not use tryptamines. Anecdotal reports suggest lithium can greatly increase the psychoactive effects of tryptamines and that it can produce very unpleasant feelings, or even symptoms similar to epileptic seizures.

    Tricyclic antidepressants, such as Trofanil (imipramine), Anafranil (clomipramine) and others, and MAOIs taken along with tryptamines, may greatly intensify the psychoactive effects.

    People with serious liver problems should avoid psilocybin mushrooms as some might have compounds that could affect the liver.


    Most all of them, most everywhere. Now understand – we are not lawyers, this is not legal advice, and the law can be complex and vary widely from place to place. When in doubt consult a licensed attorney familiar with the laws in your location.

    Seeds containing LSA might be legal to buy, sell, grow and possess in some places. But not to eat. Eating RC, HBWR and Morning glory seeds is usually illegal. Even to treat cluster headaches.

    Psilocybin mushrooms are illegal almost everywhere. They might be legal in the Netherlands, but that could change at any time. There may be countries where the government doesn’t care much about mushrooms being illegal, but you can’t count on that. In some parts of then US, you can have shrooms growing on your land, as long as you can reasonably show you didn’t know about it. But if you pick and eat them, that means you knew about it.

    In most US states (except Georgia and California), psilocybin mushroom spores can be possessed, but only for educational or scientific purposes. You can look at them with a microscope, but you’re not allowed to grow them into mushrooms. Eating spores doesn’t help – they contain no psilocybin.

    LSD is illegal everywhere for anything, unless you have a research license. Which you don’t. DMT concoctions like Ayahuasca are illegal everywhere unless you belong to certain religions in certain countries, which you don’t. And no, you can’t join these religions over the Internet.

    The best thing to do is to assume all tryptamines are always illegal, and discretion is always wise.

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