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So sorry for how your husband is suffering. You ask about what you can do right now to break the cycle. The "busting" strategy generally discussed here to break cycles would require him to be off the depakote, topamax, imitrex, maxalt, and lithium for five days, and some of those meds cannot be stopped cold turkey, they have to be tapered down. So busting might not be what you're looking for. (There are people who will tell you that all those meds are actually making things worse for him, that they are either separately or in combination causing "rebound headaches." I wouldn't be surprised if that's true. They sure don't seem to be helping.) I can only think of two things that might be effective quickly preventively, and they're more pharmas. One is a course of steroids, cortisone usually, which helps break cycles for some people. The other is verapamil, which helps some people as a preventive. He could try the vitamin D3 regimen -- https://clusterbusters.org/forums/topic/1308-d3-regimen/. That sometimes reduces a cycle or even ends it fairly quickly, but it's far from a guarantee. In the long run, it's something he probably should do that will help with the next cycle. For it to have the greatest likelihood of helping in the short run, he'd almost surely want to do some version of the "loading" that is described in that document, but that would be up to him. The only thing I have to add is that you really want to be sure that his oxygen system is optimized for highest effectiveness. A high flow rate (at least 15 lpm, but 25-plus lpm is better) to support deep and continuous breathing, and the mask designed for people with CH, which is called the ClusterO2 kit: http://www.clusterheadaches.com/ccp8/index.php?app=ecom&ns=prodshow&ref=clustero2kit. This can help him get faster aborts. Some people quickly drink down an energy shot or energy drink at the first sign of an attack, and find that it helps reduce the severity of the attack, or even sometimes abort an attack. My only concern about this is how much stuff he already has in his system from all those drugs. I wish I could be more helpful, and I hope someone else here will be.