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I was put on Verapamil 240mg to be taken 3 times a day, This made my legs feel tired all the time so I tapered mine back to one time a day in the morning. I did not notice much difference in the amount of clusters of intensity of them when I cut back. From what I hear the extended release does not work as well for some people. I also get hit as I am sleeping and just started to take benadryl along with the D3 regimen and things are starting to get better for me now. I also spent the last few nights sleeping in a recliner to try to keep my head elevated a little and that also helped. This does not answer your question but I hope it gives you a few tricks to try out.