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Hi to everyone here im new to this site but i have suffered from chronic cluster headaches for the past 6 years.There has not been 1 day in the last 6 years where i have had a single day without having any where between 3 to 8 severe attacks per day.Ive had everything that medical science has had to offer,sumatriptan ,verapamill,botox injections imgality,nerve blockers,you name it and nothing work as most of those treatments were only proven to help people that had episonic clusters but not affective for chronic cluster headaches. It got to a point where i was that depressed that thinking about suicide was my only option to end my suffering and even went as far as paying $14000 dollars to buy a funeral plan before ending my life.Then after watching several videos of people claiming that taking magic mushrooms or lsd gave far better results in very small micro dosages of 0.4 grams every 3 to 4 days had far better results than any medications with no nasty side affects what so ever i started taking shrooms and to my suprise i was getting alot less attacks per day and not as severe.Then i started looking into something that no one really ever talks about and that is ECS short for Endocannabinoid system wich is something that we are all born with our bodies naturally produce endocannabinods however as we are all different so some of us dont produce enough of this compound in our body and funnilly enough i found that people that suffer from chronic migraine and cluster headaches were the ones that were lacking this enzyme.The reason we have cluster attacks as far as i know is due to vessels in our brain become inflammed and cause the vessels in our head to swell up and put pressure on the trigeminal nerve just above our ear and intern sends severe pain signals to the nerves behind your eye your nose your cheek bone and your jaw line and in my case even my neck.So i thought well if this theory is correct then how can i increase endcannabanoids in my system that my body could not do naturally.And thats where my life changed completely.I got onto a company who was liscenced to sell very pure high grade CBD oil which had no thc in it but had the cannabanoids CBD,CBG and CBN also particularly CBG which has a very powerfull inflammitory property bound to it but also helps greatly with dealing with chronic pain, so i thought well if its such a powerfull inflammitory then if it reduces the swelling in blood vessels in my head then it will not put pressure on the trigeminal nerve.Low and behold from the first day i took a very small dosage of 0.2mlg under my tongue twice a day it was instant.For the first time in 6 years i went a full day without a cluster attack it was almost to good to be true ,but 4 weeks have past since ive been taking this particular CBD oil and my clusters have dissapeared completely.Doctors say they just dont have a cure or know why people get cluster headaches well all i can say is they need to start looking into the endo cannabanoid .I urge any one here suffering from this debilitating illness to try it i mean what have you got to loose buy giving it a try .After having chronic clusters for 6 years without have not 1 day without at least 3 to 8 attacks per day to just stop completely from taking this CBD oil cannot be just a coincidence.I feel your pain and only want to give you another possible option that is drug free with absolutely no side affects that comes with traditional medication,and if you would like to talk to me personally about how to go about it im happy to leave a number if you would like to talk to me personally.

Here's something from 2019: https://pmc.ncbi.nlm.nih.gov/articles/PMC7802413/ "As previously mentioned, it is still unclear why oxygen exhibits such good efficacy in the treatment of CH. The vasoconstrictive theory was prevalent in the early 20th century until Wolff et al. found that ergotamine constricted external carotid arteries and simultaneously relieved migrainous headaches.20 Therefore, they proposed that headache is caused by vasodilation rather than vasoconstriction. The study was published in 1938 and overturned the past theory.20 In 1961, Horton7 proposed that histamine cephalalgia was caused by the vasodilatation of extracranial vessels, and that oxygen was a vasoconstriction factor. If the vasoconstrictive effect of oxygen exists, oxygen therapy should be effective for both migraine and CH. However, the oxygen treatment is only effective for CH. In the 1980s, some studies reported a decrease of cerebrospinal flui in patients after breathing 100% oxygen as compared to breathing room air.21 Since then, animal model studies have demonstrated the protective, anti-inflammatory role of hyperoxia in microcirculatory inflammation. In 2006, Schuh-Hofer et al.11 demonstrated that hyperoxia can inhibit dural plasma protein extravasation in rats. Recent studies have suggested that CH is associated with some brain structures, including the trigeminovascular system, the cranial autonomic system, and the hypothalamus. The activation of the trigeminovascular system is thought to play an important role in the pathophysiology of CH. Goadsby and Edvinsson22 attempted to demonstrate the associations between hyperoxia and neuropeptides, and the results indicated that a significant reduction of calcitonin gene related peptide concentration in the jugular vein after oxygen treatment occurred, which suggests a possible effect of hyperoxia on trigeminal afferents. However, animal experiments have shown that oxygen does not directly act on trigeminal afferents, but appears to play a key role at the parasympathetic pathways.23 At present, studies assume that oxygen may act as a terminating factor in CH attacks. More research is needed to clarify the specific mechanisms of oxygen treatment for CH. Table 1. The history of oxygen used for cluster headache Study Year Findings Alvarez et al.15 1940 First use of oxygen for headache at a flow rate between 6 and 8 L/min. Horton16 1952 First description of oxygen used for histamine cephalalgia. Horton17 1955 Oxygen treatment in 1176 patients with histamine cephalalgia. Horton7 1961 He raised the vasoconstrictive effect of oxygen in histamine cephalalgia. Kudrow et al.18 1981 First systematic study on oxygen used for cluster headache. Fogan et al.12 1985 Crossover study found that oxygen was more effective than room air. Cohen et al.19 2009 Oxygen at 12 L/min, as well as at 7 L/min, was effective. Open in a new tab Figure 1. Open in a new tab The possible mechanism of oxygen in cluster headache. Note: TCC: Trigeminal cervical complex.