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One of very common topics in finnish CH communities is regular use and especially over-use of triptans rendering oxygen ineffective. I have also experienced this myself. Some notice oxygen is less effective when usual and for some it does not work at all. That's a place where you don't want to be. But don't worry, when you stop using triptans the oxygen response will come back. There are also reports on other medications, especially when the overall medication burden is heavy. I see people all the time who have given up on oxygen and they are doing loads of prescription medicines simultaneously and attacks keep on coming.