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xxx

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Everything posted by xxx

  1. xxx

    Started D3 Regimen three days ago

    Dehabel, Off hand it appears you're starting to respond to the anti-inflammatory regimen. Steroids tend to slow the response to vitamin D3 and all the cofactors. That said when push comes to shove, steroids do work... it's a tradeoff. Oxygen and a week to 10 day course of Benadryl (Diphenhydramine HCL) at 25 mg every 4 hours during the day and at bedtime will help. Just be careful and not drive as this much Diphenhydramine will make you drowsy. Many CHers who need to drive during the day have found it's best to wait until you've home for the day then take 50 mg as you walk through the door and another 50 mg at bedtime. Take care and please keep us posted. V/R, Batch
  2. xxx

    Benadryl

    Hey Dehabel. You're not annoying. You've received some great answers about Benadryl (Diphenhydramine HCL). Diphenhydramine is classified as an anticholinergic - a chemical that blocks the action of the neurotransmitter acetylcholine (ACh) at synapses in the central and the peripheral nervous systems. Accordingly, it should only be taken for a week to 10 days dosing at 25 mg every 3 to 4 hours during the day and at bedtime. As Diphenhydramine a also classified as a first-generation antihistamine, it's antcholinergic properties will make you drowsy so you should avoid driving while taking this much. If you do need to drive during the day, wait until you're home for the day then take 50 mg as you walk through the door and another 50 mg at bedtime. If an allergic reaction is contributing to the frequency, severity and duration of your CH, Benadryl (Diphenhydramine HCL) should start providing relief in a few days. If there's been no change in your CH patterns, after a week, discontinue.' The Diphenhydramine mechanism of action is relatively simple. As a first-generation antihistamine, it crosses the blood brain barrier (BBB) into the brain and blocks histamine H1 receptors at the genetic layer in neurons throughout the brain and in particular, the trigeminal ganglia where histamine released as a result of an allergic reaction, triggers the expression of Calcitonin Gene-Related Peptide (CGRP) and Substance P (SP) another neuroactive peptide. These are two of the four neuropeptides responsible for the neurogenic inflammation and pain we know as cluster and migraine headache. It is also important to note that second- and third-generation (non-drowsy) type antihistamines cannot cross the BBB to block histamine H1 receptors in neurons throughout the brain and CNS so will be less effective. I look at Benadryl (Diphenhydramine HCL) as a diagnostic tool. If it works to reduce the frequency, severity and duration of your CH, histamine is the likely culprit. If it doesn't work, the odds are higher histamine is not your problem. Many of us have found adjusting the vitamin D3 intake to be a more effective and much safer method of controlling and preventing CH than taking Benadryl (Diphenhydramine HCL). The following photo illustrates the supplements by brand in the basic anti-inflammatory regimen CH and MH preventative treatment protocol. All are taken daily with the largest meal of the day at the doses shown for the first 12 days. After that, you reduce the vitamin D3 dose (Bio-Tech D3-50) to one capsule a week and continue taking everything else daily. There's a lot more to this regimen and you'll need to discuss it with your PCP/GP before starting it, when asking for labs of your serum 25(OH)D3, calcium and PTH (Parathyroid Hormone). CHers who stick with the brands illustrated below tend to have higher favorable response rates. With the exception of the Bio-Tech D3-50 50,000 IU water soluble vitamin D3 that I added in place of the 5,000 IU oil-based liquid softgel vitamin D3 formulations in July of 2018 and the Methyl Folate + I added in place of the vitamin B 50/100 complex in January of 2019, the rest of these supplements have remained unchanged since 16 December, 2011. The rationale for these changes is due to the higher bioequivalence and improved efficacy in controlling and preventing CH and MH these two supplements offer. Readers of my webpage at vitaminDwiki.com at the following link have downloaded 51,216 copies of the anti-inflammatory regimen CH and MH preventative treatment protocol since I posted it in January of 2017. https://vitamindwiki.com/Cluster+headaches+substantially+reduced+by+10%2C000+IU+of+Vitamin+D+in+80+percent+of+people You will also find a copy of this protocol at the above link. If you're interested in starting this CH and MH preventative treatment protocol please take a copy to your PCP/GP to discuss and ask for lab tests of your serum 25(OH)D3, calcium and PTH before starting this treatment protocol. You can also download a copy of this treatment protocol by clicking on the following link. http://www.vitamindwiki.com/tiki-download_wiki_attachment.php?attId=7708 I've sent you a PM with more information about this CH and MH preventative treatment protocol. That you experienced an 8-year haitus, free of CH tells me you're a good candidate for the anti-inflammatory regimen. It's likely something changed in your diet or there was a decrease amount of summer sun you were getting that caused your CH to return. This bring us to the burning questions you may have... Will this treatment protocol be effective for me and is it safe? The best answer I can provide comes from data compiled from the online survey of 313 CHers who have started this treatment protocol since 16 December, 2011 when I placed this survey on the Internet. The year over year efficacy of this treatment protocol between December of 2011 and December 2018, finds 80% of CHers experiencing a significant reduction in the frequency of their CH from 21 CH/week down to 4 CH/week in the first 30 days after starting it. 53% of CHers starting this regimen experience a lasting cessation of CH in the first 30 days. It's important to understand that this regimen needs to be taken daily in order to experience results like this. Most of us who take this regimen daily, consider it a way of life that keeps us CH pain free. Moreover, the health benefits that come from taking this regimen are hard to ignore. The exciting news comes from CHers who started this survey during 2019 after I changed the suggested form of vitamin D3 to the Bio-Tech D3-50. The efficacy of this protocol during 2019 finds over 90% of CHers experiencing a favorable response with a significant reduction in the frequency of their CH in the first 30 days from 21 CH/week down to 4 CH/week and 67% of CHers experiencing a complete and lasting cessation of their CH in the first 30 days. I've tracked results from all open source RCTs of CH prophylaxis and none of them come even close to this level of efficacy. Moreover, since this treatment protocol went online, there have been no reports of hypercalcemia, a.k.a., vitamin D3 intoxication/toxicity nor have there been any adverse events reported that required medical attention. The following charts illustrate data from 313 CHers who started this treatment protocol since December of 2011, then took this survey ≥ 30 days later. The following chart illustrates the normal distribution (green curve) and cumulative probability (blue curve) of lab results for serum 25(OH)D concentrations after ≥ 30 days on this regimen. The following two charts illustrate the time to respond after starting this regimen. Taken in concert with the efficacy data, the above charts make a clear case that an inverse relationship exists between the frequency of CH and 25(OH)D3 serum concentration. In simple terms, when the frequency of CH is high, the 25(OH)D3 serum concentration is low around a mean of 24 ng/mL and when the CH frequency is low or the CHer is CH pain free, mean 25(OH)D3 serum concentration is higher around 80 ng/mL. This is why it's important to obtain lab tests of your serum 25(OH)D3, calcium and PTH before starting this regimen and again 30 days after starting it. You can thank the 313 CHers who took the time to take this survey. They came from 35 countries around the world. Take care and please keep us posted should you decide to start this treatment protocol. V/R, Batch
  3. xxx

    My list of supplements

    The experts at Orthomolecular have a very similar immune boosting protocol to help guard against viral infections. https://orthomolecular.activehosted.com/index.php?action=social&chash=6c4b761a28b734fe93831e3fb400ce87.161&s=b6603c369765a26b8432c6fde3807447 FOR IMMEDIATE RELEASE Orthomolecular Medicine News Service, June 4, 2020Personalize Your COVID-19 Prevention An Orthomolecular Protocol by Michael J Gonzalez, NMD, PhD Recommended supplementation (basic): Take immune-optimizing supplements. There are a number of supplements you can take that will improve your immunity to disease. Multivitamin and mineral, one daily Vitamin C 1,000 mg, three times daily, reduce if it causes laxative effect. Vitamin D 2,000 - 5,000 IU daily depending on body weight, 10,000 IU daily for the first 2 weeks Zinc 30 mg daily Magnesium 500 mg daily (in malate, citrate, or chloride form) Selenium 200 mcg daily (also contained in many multivitamin supplements) Probiotics >30 billion a day Quercetin 500 mg daily NAC (N-Acetyl-Cysteine) 500 mg daily Melatonin 1-5 mg daily, depending on individual tolerance and need Other suggested supplements: Echinacea, astragalus, rhodiola, maitake, shitake, ginger, garlic, elderberry, vitamin A, lipoic acid, CoQ10, vitamin E (mixed tocopherols with all four tocotrienols). Take care, V/R, Batch
  4. xxx

    My list of supplements

    Hey Dana, Howz the head? Your supplements look great! There are a few more important supplements you can add to help boost your immune system functions to prevent viral infections beyond that made possible by vitamin D3 and its cofactors. You've already got 4 of the 7 covered so all you really need to add are the 50 mg/day zinc picolinate, 800 mg/day Quercetin and at least 3 grams/day (1g 3XDay) vitamin C (Ascorbic Acid). Zinc supports a number of important enzymatic reactions. It also blocks virus from entering cells lining lung alveoli. When used with quercetin that acts as an ionophore to transport water soluble zinc ions through epithelial cell walls forming the alveolar membrane. Once inside cell cytoplasm, zinc blocks viral replication. Vitamin C is a virus and bacteria killer from the word go. The liposomal (fat wrapped) vitamin C has a longer serum half-life than regular ascorbic acid, so taking one of these capsules every 3 hours throughout the day makes for a good defense against viral, bacterial and fungal infections. Double or triple the vitamin C dose if you feel an infection approaching. Take care, V/R, Batch
  5. Pebblesthecorggi, Understand... However, as there is no down-side safety issue in taking 3 grams/day vitamin C or 5000 IU/day vitamin D3, and there is more than sufficient up-side potential based on substantial evidence in their efficacy in preventing and treating colds and flu, there's much to gain an nothing to lose at a cost of 12 cents/day. Nothing is 100% effective or certain save for death and taxes. Moreover, as none of us gets out of here alive, at 75, my goal is to maintain the best quality of life possible. I take far more vitamin C and vitamin D3 than listed above. Joyce and I have been taking the anti-inflammatory regimen since I developed it in October of 2010. Neither of us has had the flu since then and our incidence of colds is down to one every 3 to 4 years. We've also had school age grand kids and their friends running around the house dripping with cold and flu bugs several times a year so we don't live in a bubble. Take care, V/R, Batch
  6. Hey Microdosing, Great question and you're OK! There's a very simple reason why the nostril on the hit side gets the gush and stuffy during a CH. The pain and neruogenic inflammation during an active CH hit triggers the eye on the hit side to water. This starts happening between Kip-5 and Kip-7 pain levels for most CHers and the flow increases as the pain goes up. The tearing caused by CH hits ≥ kip 5 drains down the nasolacrimal ducts at the inside corner of the eye next to the nose on the hit side. The saline tear fluid exits these ducts into the nasal cavity, as its name implies. That means tears from the eye start running out the nose. The lining of the nasal cavity on the hit side reacts by swelling and this gives us the stuffy feeling. So much for today's lesson on anatomy and pathophysiology of a CH. There is a solution to this problem... For the CHers who know what I'm about to say... Wait for it... I would start taking the anti-inflammatory regimen. You can download the posted version of this CH and MH preventative treatment protocol at the following vitaminDwiki.com link. http://www.vitamindwiki.com/tiki-download_wiki_attachment.php?attId=7708 For reference, readers of my webpage at vitaminDwiki.com have downloaded 47,321 copies of this CH and MH preventative treatment protocol since 21 Jan, 2017. That's an average of 40 downloads a day. Word on the efficacy of this regimen is getting out. Even if you're not ready to start this regimen or you're satisfied mm are controlling your CH effectively, taking 3 grams/day vitamin C and at least 5000 IU/day vitamin D3 can help build a strong immune system. MM can't do that. Vitamin C supports your immune system. Vitamin C helps to kill viruses and reduces the symptoms of infection. It's not a COVID-19 "cure," but nothing is. It might just save your life, though, and will definitely reduce the severity of the infection. If someone tells you it's not proven, consider two things: 1. Nothing is proven to work against COVID-19, because it is a new virus First identified and named by the WHO 11 Feb Its genome first sequenced on 25 Feb, No RCTs of the COVID-19 coronavirus have been completed, but a lot have started. 2. Vitamin C has worked against every single virus including influenzas, pneumonia, and even poliomyelitis. See the following link for details. https://orthomolecular.activehosted.com/index.php?action=social&chash=a5e00132373a7031000fd987a3c9f87b.150&s=b6603c369765a26b8432c6fde3807447 Take care and take vitamin C, V/R, Batch
  7. xxx

    Influenza and CH

    Hey Bee, I strongly support the use of mm and the other things discussed at this site. I've seen them work effectively up close and personal, busting CH cycles when even vitamin D3 wasn't effective. I just don't have any expertise in this area so leave that to the experts here. I also spent a year helping Dr. John Halpern, MD, get the BOL used in his study into a "Fast Track" approval process at the FDA. As a 75-year-old retired Navy fighter pilot, the disciplines needed to fly fighters at 1,000 miles an hour, fight bad guys in high-G combat maneuvering and land on an aircraft carrier day and night demanded a complete avoidance of any substance that altered my neurological functions including memory and split-second reflex response. Those disciplines are still with me today. Accordingly, I rely on vitamin D3 and its cofactors to control and prevent CH and migraines as this combination carries no mind altering baggage. Moreover, in the 9 years I've been a member here at Clusterbusters, I've seen many cases where a combination of mm and vitamin D3 had a synergistic effect of busting cycles much faster than mm or vitamin D3 could do by themselves. Take care, V/R, Batch
  8. xxx

    Hey Batch!!!

    Vitamin D3 stimulates the synthesis of melatonin naturally.
  9. xxx

    Influenza and CH

    Hey Igdc, Good comments. My experience with CH that dates back to 1994 with my first bout with CH and I've been chronic since 2005. What I've found is the severity of this disorder is compounded by vitamin D3 and magnesium deficiencies and there's a clear inverse relationship between CH frequency and serum 25(OH)D3, the serum level metabolite of vitamin D3 that's measured by lab tests. Well over 2500 CHers are now taking the anti-inflammatory regimen with 10,000 IU/day vitamin D3 and cofactors to prevent their CH. The updated version of the supplements called for in this regimen are illustrated in the following photo of what my wife and I have taken daily since October of 2010. I suggest these supplements to CHers all over the world. If you add 3 grams/day vitamin C, t.i.d. (one gram 3 times a day), you'll have an effective preventative for colds and flu... and I'm confident the COVID-19 novel coronavirus as well. The last two graphics apply. On a related note, my niece has asthma and has been taking this regimen daily for the last 9 years through two pregnancies and breastfeeding. Results: two flawless pregnancies, deliveries and two exceptionally healthy babies with T-Rex immune systems. She's taken one of the Bio-Tech D3-50 50,000 IU capsules of water soluble vitamin D3 every 3 to 4 days for the last four years since she stopped all Rx meds for asthma, to keep her asthma in remission and that has proven to be very effective. Take care and please keep us posted. V/R, Batch
  10. xxx

    Portable oxygen concentrator issued by VA

    Hey Mark, Thank you for your service. The Redneck Reservoir bags work like a champ with aborts running around 7 minutes with the procedure outlined in my previous post. I made the one shown in the photo while salmon fishing in Pelican, AK, a fish camp with population 76 in the winter so there are no medical oxygen suppliers. Fortunately, there are lots of welders and plenty of welding oxygen. I made up two such Redneck Reservoir bags last June when an allergic reaction to mold spores kicked me out of a CH remission that had been running for over a year CH pain free. I filled these bags by sticking the tip of a cutting torch in the plastic bottle and turned on only the oxygen. It took 4 days loading vitamin D3 at 50,000 IU/day plus Benadryl at 25 mg every four hours throughout the day to stop the CH beast from jumping ugly. Even with the CH hist coming at night, they did not stop me from salmon fishing during the day... Take care and please keep us posted. V/R, Batch
  11. xxx

    Portable oxygen concentrator issued by VA

    Hey Marine, I'm a 75-year-old retired Navy fighter pilot and I'm on Tricare for Life as well. I've never had any problems getting M-Size oxygen cylinders or a few of the smaller E-size cylinders with a CGA-870 regulator. Ask for a CGA-870 regulator with selectable flow rates up to 25 liters/minute. If they tell you they don't have any with flow rates that high, buy one as suggested. Better yet, make yourself a DIY Redneck Oxygen Reservoir system out of a clean empty plastic Coke or Gatorade bottle (with cap) and bottom cut off, a clean kitchen trash bag, tubing from a disposable oxygen mask, some electrician's tape and some Duck Tape. The following diagram should help. When you're done building this Rube Goldberg contraption it should look like the following Redneck reservoir bag without the oxygen tubing. If you've done a good job with the tape so the seals are all gas-tight so it holds oxygen overnight without deflating, and you use the right breathing procedures, one of these Redneck oxygen reservoir systems is good for three aborts. These contraptions have zero inhalation resistance making them easier to inhale from than an oxygen demand valve. The procedure is simple. You hyperventilate with room air at forced vital capacity tidal volumes for 30 seconds then remove the cap from the Coke bottle and inhale a lungful of oxygen from the Redneck reservoir bag and replace the cap. Hold the lungful of oxygen for 30 seconds then keep repeating the complete sequence until the CH pain is gone. This usually takes an average of seven complete cycles (7 minutes). Forced vital capacity means exhale forcibly until it feels like the lungs are empty - they're not - without delay, do an abdominal crunch like doing sit-ups and hold the squeeze on every exhalation for a second. On the final exhalation hold the squeeze for three seconds. This will squeeze out a half to full liter of exhaled breath highest in CO2 content. Blowing off CO2 like this is an important part of aborting CH. If you're doing this procedure and breathing technique properly, you should start feeling a slight tingling or prickling sensation in the lower legs and feet, hands, face and lips after the 3rd to 4th cycle with room air. You may even sense a chill across the lower back above the belt line. These sensations are called parasthesia, an indication you've pushed you system into respiratory alkalosis, a temporary condition where the blood CO2 content is below normal. These sensations are caused by capillaries and microvasculature in the skin constricting. This is what we want to happen in the trigeminovascular system as it speeds up the abort. If you watched the movie The Andromeda Strain, respiratory alkalosis is what saved the baby. This is an important mechanism that also aborts CH. A low blood CO2 content means the blood is more alkaline with a higher pH than normal. This is also an important CH abort mechanism as the elevated pH triggers blood hemoglobin to have a greater affinity for oxygen and off load CO2 faster as blood passes through the lungs. The result is a super-oxygenated flow of blood to the brain and this is also an important part of the CH abort mechanism. This method of oxygen therapy as a CH abortive is just as effective as using an oxygen demand valve. I hold a patent (now expired) on the demand valve method of therapy in aborting CH. The big difference is in the amount of oxygen consumed. Hyperventilating with an oxygen demand valve until the abort will consume 250 to 300 liters of oxygen. Using the above procedure consumes ~ 25 to 30 liters of oxygen/abort. A redneck reservoir bag is a lot easier to haul around in the back seat of your car than an E-Size medical oxygen cylinder. Take care and please keep us posted. V/R, Batch
  12. xxx

    Hey Batch!!!

    Spiny, There are two changes to the supplements listed in the posted version of this treatment protocol that will appear in the updated version I hope to have available later this month. They include switching to the Bio-Tech D3-50 50,000 IU water soluble form of vitamin D3 that's suggested at a dose of one (1) D3-50/week as the initial maintenance dose. Rationale: The Bio-Tech D3-50 is proving to be faster acting with a higher bioequivalence in elevating serum 25(OH)D3 than the same dose of the oil-based liquid softgel vitamin D3 formulations. The D3-50 is also less expensive at one 23 cent capsule a week or ~3 cents/day. Bio-Tech D3-50 https://www.amazon.com/Bio-Tech-Pharmacal-D3-50-100-Count/dp/B000A0F2B2?ref_=ast_bbp_dp&th=1&psc=1 https://www.iherb.com/pr/Bio-Tech-Pharmacal-Inc-D3-50-Cholecalciferol-100-Capsules/55186 The other change is a switch to Methyl Folate + (vitamin B complex) in place of the vitamin B 50/100 complex. Rationale: This form of Folate and B complex appears to have a higher bioequivalence in preventing CH and MH. These are also the same B vitamins called for in the Coimbra protocol used to prevent MS and other autoimmune disorders. Methy Folate + Vitamin B Complex https://www.amazon.com/Bioactive-Formulated-Pharmaceutical-Methylcobalamin-Synergistically/dp/B01MQJVHHC?ref_=ast_bbp_dp https://www.iherb.com/pr/Doctor-s-Best-Fully-Active-B-Complex-with-Quatrefolic-30-Veggie-Caps/50940?refid=1c105ef4-ca2e-4f09-bcc7-bddc10c426b9&reftype=rec Take care and please keep us posted. V/R, Batch
  13. Hey NightOwl, CHfather is spot on with his info. I just sent you a PM with enough of the other info on this regimen to get you started. Please shoot me a PM response when you read my PM to you. Take care and please keep us posted. V/R, Batch
  14. xxx

    Hey Batch!!!

    Hey Spiny, You can find the posted version of the anti-inflammatory regimen CH and MH preventative treatment protocol on my webpage at the following vitaminDwiki.com link: http://www.vitamindwiki.com/tiki-download_wiki_attachment.php?attId=7708 Take care and please keep me posted. V/R, Batch
  15. xxx

    Emgality and CCH - bummer trial results

    For 2019, the 30-day efficacy jumped to over 90% of CHers starting this regimen experiencing a significant reduction in CH frequency from a mean of 21 CH/week down to a mean of 4 CH/week. Better yet, over 65% of CHers starting this regimen experienced a lasting cessation of CH in the first 30 days. I attribute this increase in efficacy to the switch to the Bio-Tech D3-50 50,000 IU water soluble vitamin D3. That's the only thing that's changed since July of 2018. I know the medical evidence purists will say an open label observational study rates a low level of medical evidence. To that I say, this is not your every-day average observational study. It's been running for over 8 years with over 320 participants and the year-over-year 30-day efficacy has remained constant at ≥80% for a favorable response and ≥50% for a lasting complete cessation of CH in the first 30 days. Moreover the generalizability of these results is very good as participants have come from 35 different countries around the world. That's not to mention all the health benefits made possible by the anti-inflammatory regimen at a cost of ~ 50 cents/day or $15/month USD. The Emgality cost is $550/month and it carries some onerous adverse side effects. Bottom line... The Anti-CGRP mAbs are never going to work as they cannot pass through the blood brain barrier to reach the site of action in neuronal nuclei within the trigeminal ganglia where CGRP is expressed. At best all the Anti-CGRP mAbs can do in lower the CGRP serum concentration. Here's the math and molecular biology behind this statement. These mAbs have a molecular mass of 150 kDa (150,000 Daltons) but the fenestration (windows) through the BBB have a maximum aperture of 400 Da. That makes the monoclonal antibodies 375 time too big to pass through the BBB windows. A molecule of vitamin D3 has a molecular mass of 385 Da so it passes readily through the BBB and into neuronal nuclei to do its thing through genetic expression to down-regulate (decrease) the expression of CGRP, SP, VIP and PACAP. The Anti-CGRP mAbs only react to CGRP.
  16. Dear Lúthien, The endocrine system and its endocrine hormones play a significant role in both cluster and migraine headache. The problem is no two women behave alike during pregnancy or while taking birth control pills. One of the best ways to get on an even playing field so to speak and get your CH under control, is to start taking vitamin D3 plus its cofactors. The first step in this process is to see your PCP/GP for lab tests of your serum 25(OH)D3, calcium and PTH (parathyroid hormone). Odds are high you're vitamin D3 insufficient/deficient. As Chers, we need our 25(OH)D3 between 70 and 100 ng/mL so be sure to ask for the acutal 25(OH)D3 measurment and not just your doctor's interpretation of the results. As the normal reference range for this lab test is 30 to100 ng/mL so most physicians will say 31 ng/mL is normal... which is true for rickets, but not CH.' Even though you've experienced a CH pain free response using a low-dosage estrogen patch, there's no guarantee it will continue. You can find a download copy of the anti-inflammatory regimen CH and MH preventative treatment protocol at the following VitaminDWiki link: http://www.vitamindwiki.com/tiki-download_wiki_attachment.php?attId=7708 This regimen has a wonderful efficacy with 80% of CHers responding with a significant reduction in the frequency of their CH from a mean of 21 CH/week down to a mean of 4 CH/week in the first 30 days. 52% of CHers starting this regimen experience a complete and sustained cessation of their CH in the first 30 days after start of regimen through the end of 2018. Both figures of efficacy jumped by 10% in 2019 after I started suggesting CHers switch to the Bio-Tech D3-50 50,000 IU water soluble vitamin D3 in July of 2018. There have been no reports of hypercalcemia, a.k.a., vitamin D3 intoxication/toxicity since I began posting about the efficacy of this regimen in December of 2010. Take care and please keep us posted. V/R, Batch
  17. Hey Vipul, The possibility exists that the sinusitis mentioned in your MRI DX is secondary to CH. In other words, the sinusitis is a direct result of multiple CH which cause all the sinus on the CH side to gush with mucus. On the other hand, it could also be just a coincidence with no real correlation. The possible involvement of the RCA (right superior cerebellar artery) with the trigeminal ganglia resulting in neurovascular conflict, mentioned in your MRI DX, is frequently associated with trigeminal neuralgia. This is where the RCA is physically wrapped around the trigeminal ganglia putting pressure on it and a creating a chaffing action that sensitizes the trigeminal ganglia stimulating pain very similar to CH. I'm a 75-year-old retired Navy fighter pilot so clearly not a doctor or qualified to read MRI imagery. That said, I read studies of CH voraciously. While there are clear cases of CH being secondary to lesions in and around the trigeminovascular complex, the majority of CH are primary. The human body is totally amazing in its capacity to heal itself if given the right nutrients. After all, it's been doing this for thousands of years before modern medicine or we wouldn't be here. I recall our family doctor telling me to remember the alphabet when it comes to vitamins (A, B, C, D, E). Take care and please keep us posted. V/R, Batch
  18. Hey Cast Iron, I made several trips to your country between 1997 and 2003, mostly to Den Haag to work at the SHAPE Technical Centre. Den Haag was great and so was Amsterdam, but I loved Scheveningen. Great little seaside restaurants with wonderful food. Getting to your problem, I suspect you are vitamin D3 deficient and that deficiency is contributing to the frequency, severity and duration of your CH. Baseline lab tests by CHers reporting in this survey, before starting this regimen are illustrated in the following normal distribution curve. The normal reference range for the 25(OH)D3 lab test is 30 to 100 ng/mL (75 to 250 nmol/L). Most CHers experience a favorable response to this regimen with a mean 25(OH)D3 serum concentration around 80 ng/mL. We've made some important changes to the anti-inflammatory regimen and treatment protocol. The most significant change occurred in July of 2018 with the switch from the oil-based liquid softgel vitamin D3 formulations to the Bio-Tech D3-50 50,000 IU water soluble vitamin D3. Several of us found it faster acting with a higher bioequivalence in elevating serum 25(OH)D3 than the same dose of the oil-based liquid softgel vitamin D3 formulations. The following photo illustrates the supplements I take and now suggest to other CHers. Most CHers in Europe have found they can order these supplements through iherb.com. I just crunched the numbers from the online survey of CHers taking this regimen as of 31 December 2019. There was a significant increase in the efficacy of this regimen during 2019. Over 90% of CHers starting this regimen in 2019 experienced a significant reduction in the frequency of their CH from 3 CH/day down to 4 CH/week in the first 30 days. Moreover, 67% of CHers starting this regimen in 2019 experienced a sustained cessation of CH symptoms in the first 30 days. Although I can't say for sure, it appears this increase in efficacy is likely due to the switch to the Bio-Tech D3-50 as nothing else has changed. I track all the other CH prophylaxis and none of them come close to this level of efficacy, let alone at a cost around 50 cents/day USD with no adverse events. I've made some changes to the treatment protocol that include new target 25(OH)D3 serum concentrations and longer vitamin D3 loading schedules to reach these new targets. These changes will appear in the updated version of this treatment protocol I hope to post on my web page at vitaminDwiki.com later this month. These changes include: New TGT 25(OH)D Concentrations - New Loading Schedules Episodic CHer 80 to 100 ng/mL. - Load at 50,000 IU/day for 12 - 14 days Chronic CHer 90 to 120 ng/mL. - Load at 50,000 IU/day for 14 - 16 days Migraineurs 100 to 140 ng/mL - Load at 50,000 IU/day for 16 - 18 days It's important to understand these suggested 25(OH)D3 serum concentration target ranges and loading schedules are a starting point for the average ECHer, CCHer and migraineur. Many CCHers (like me) will require a higher 25(OH)D3 serum concentration, a longer period of loading at 50,000 IU/day and a higher maintenance dose to experience and maintain a CH pain free response. In practice, CHers can start the accelerated vitamin D3 loading schedule and stay on it until they experience a favorable response then add an extra two days at 50,000 IU/day to build a reserve then drop back to a maintenance dose of one (1) D3-50 a week. I've also added some other supplements needed by migraineurs and some chronic CHers taking this regimen that are illustrated in the following photo of what I take daily. There are other go-to supplements that can be taken in the event the above are not resulting in a favorable response, but I think you have enough to go on should you decide to try this regimen again. Take care and please keep us posted. V/R, Batch
  19. We don't get many unannounced visitors...
  20. Hey Dana, Glad to hear you're CH pain free. I only wish we could send you some rain. My rain gauge indicated 15 inches for January. It's looking like Jurassic Park around here with all the moss and sword ferns. My driveway/logging road to the house on 4 Jan. Take care, V/R, Batch
  21. Hyperventilation with room air until you reach respiratory alkalosis can be helpful in lowering the pain of CH but it too, does nothing to replete a vitamin D3 deficiency.
  22. Getting cold will not replete a vitamin D3 deficiency.
  23. Hey Dana, Thanks for the feedback. I'm happy to hear you're CH pain free and feeling good. Are you taking the Bio-Tech D3-50 form of vitamin D3? After over 9 years working with both episodic and chronic CHers taking this regimen of vitamin D3 and cofactors daily, nearly all episodic CHers who stay on this regimen year round report they sail through their usual episodic cycles CH pain free. Take care and please keep us posted. V/R, Batch
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