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  1. Hey Jimmy, How much vitamin D3 are you taking and have you had the 25(OH)D lab test lately? Most CHers taking the anti-inflammatory regimen need 10,000 IU/day vitamin D3 and an average serum 25(OH)D concentration response around 80 ng/mL for a CH pain free response. The following chart illustrates the normal distribution and cumulative probability of 25(OH)D lab results reported by 257 CHers in the online survey taking an average of 10,000 IU/day vitamin D3. The blue S-shaped sigmoid cumulative probability curve provides a good approximation of dose response as measured by serum 25(OH)D concentration. In simple terms, as 90% of CHers reporting in this survey responded at a 25(OH)D serum concentration of 120 ng/mL. What this curve tells us is if the CHer hasn't responded at a lower 25(OH)D serum concentration taking 10,000 IU/day vitamin D3, increasing the vitamin D3 dose above 10,000 IU/day for a higher 25(OH)D response will likely result in a significant reduction or complete cessation of CH. Take care and please keep us posted. V/R, Batch
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