Nice to wake up on a Saturday morning and see that the amazing spiny has already done what needed doing.
This is the file about splitting Imitrex injections: https://clusterbusters.org/forums/topic/2446-extending-imitrex/
This the mask she referred to: http://www.clusterheadaches.com/ccp8/index.php?app=ecom&ns=prodshow&ref=clustero2kit
This is an alternative approach to using oxygen, not requiring a higher-flow regulator or the special mask, that has worked well for many: https://clusterbusters.org/forums/topic/4919-batchs-hyperventilation-red-neck-bag/
With more effective oxygen, the D3 regimen, and the other strategies spiny mentioned (energy shot, melatonin), things should get a lot better.
FWIW, the agents used for busting don't show up on any standard drug-testing panels. In the file about LSA, you'll see that the seeds are legal to purchase and legal to possess. He could also try kudzu root, which is 100% legal and has been shown to be quite effective.