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Hi Matthew. I am not aware if anyone trying this. I highly suspect that there are different ingredients in the nasal vs the injection. So, I doubt that it would be a good thing to try!!!! You could spend some time on the Net to see what are the ingredients of each. They likely are rather different due to the method of administration at the very least. Please, take care! What else are you doing for your CH? O2? Energy drinks? Are you Episodic? Have you tried the D3 Regimen? ATB!

Thank you for this post! I've ordered this nasal spray and will see if it will help me too.

Hi Tom, I have chronic paroxysmal hemicrania. I do not have attacks all the time but in recurrent blocks of 2-3 days. When it's active, I can easily do +20 attacks a day. Average attack duration is 10 minutes. I have also migraine and such an attack series always start with a light migraine that then escalates. 100 mg indomethacin stops it completely, I mean the hemicrania attacks... the migraine is not affected by that and just continue. For migraine, I use oxygen which -very atypical- abort nearly all my attacks. Oxygen and indomethacin make me now nearly 100 % painfree. what doses of indocin do you take ? I had no effect on 75 mg, 150 was much better but I did 3 x 50. I changed that to start with 100 and then 50 8 hours later and that worked much better ! So I would advise you to experiment a bit with how you divide the doses. I have no side-effects from indocin and it cancels the attacks completely; which should normally be the expected result if you have CPH. You can try oxygen but I can tell you for CPH, it will make the headache a bit more bearable but don't expect a miracle. And anyway, attacks only take 10 min so until you opened your bottle and start breathing; the attack is already over. When I have CPH attacks I never use oxygen. Something that often can work for CPH is topiramate. Maybe you can ask to give that a try. But really, this ugly indocin should be your friend. Previous month, I had one occasion where I felt a new series was coming but I did not take my 100 mg indocin on time... well, a few hours later I ended up in the ICU begging they would do whatever to stop the pain ! siegfried

I have been researching oxymetazoline for some time now and have been using as a substitute for sumatriptan for nearly 3 years. I am 100% certain that this aborts my cluster headaches. Oxymetazoline as an α-adrenoceptor agonist, however it works as a full and potent agonist of serotonin receptor types 5-HT1A, 5-HT1B AND 5-HT1D, and is a partial agonist of 5-HT1C. Sumatriptan works as an agonist of serotonin receptor types 5-HT1B and 5-HT1D. It is believed that sumatriptan aborts cluster headaches because of cerebral vasoconstriction caused by its action as an agonist on serotonin receptor type 5-HT1D So I firmly believe oxymetazoline aborts cluster headaches. So far you are my first confirmation. Spread the word

Hi Mark - I had a very similar experience as you described. Emgality worked at first and then it made the headaches worse. When I stopped the medication my regular cycle came worse than ever and for the full amount of weeks as before but totally off season. I feel that Emgality just pushed my cycle and made it worse.