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.....seems countintuitive ...N20 described as a "potent cerbral vasoldilator" which is just the opposite of what we want. would seem similar to nitroglycerine which can be used diagnostically to precipitate a CH hit.... ...on the other hand....thc is discussed on every CH board i've ever been on.... and while it too is a potent vasodilator, there are folks who swear by its use. though i do not recall as an abortive (yikes, smoking tobacco for me during a hit was damn near suicide)... ....can only wildly speculate that vasodilation throughout body might reduce the pressure on the trigeminal nerve....but this is way beyond my knowing....

....thank you for this Ricardo....monoclonal antibodies actually saved my life for another condition.....but it was a trade off, with long term consequences not fully revealed/discussed prior. i would (and might have to) do it again....but INFORMED consent this time.....

Hello, About 2 weeks back, I was suffering some very nasty attacks. 2 to 3 a day each lasting an hour reaching extremely high pain levels. I happened to speak to a friend who is a homeopathy doctor. I was surprised to hear from him that cluster headaches were curable in homeopathy. He spoke to me for an hour on everything except my attacks including emotional issues that I may have had in the past. He sounded very confident. He gave me some meds. Next day onwards my pain levels came down. 3 days later my attacks became less frequent. 2 weeks into the treatment, my attacks have almost stopped. I get an odd minor attack once in a while but no full blown attack now. I know fully well that CH is never going to go away. But I am pleasantly surprised at the effectiveness of homeopathy in treating CH. I will continue the meds and report feedback here. Pain free wishes to all. Har Har Mahadev Vipul

Dr. Lawrence Robbins of the Robbins Headache clinic recently came out with an article on the CGRP mononclonal antibody drugs such as Emgality. He has been one of the biggest prescribers of these meds and to me, he seems like the most reputable, qualified doctor that we have in headache medicine right now. Technically the subject of his article was not the CGRP drugs, it was more about the system that we have in place to get accurate info to patients about medications. And he titled the article "The system is broken". And he used the CGRP meds like Emgality as an example of just how broken the system is. He says this because we originally were told that these meds were about as close to side effect free as you can get, but now we are seeing a very different reality. He says that at this point we have close to 6,000 cases of serious adverse events, meaning that people either ended up with a life threatening condition or needing hospitalization. He called this amount "staggering" and he also said it is the tip of the iceberg and that in reality, the numbers are most likely much much higher. And if you listen to the huge amount of patients that have had horrible reactions from these meds then what Dr. Robbins is saying makes sense. Because you find that most of them have doctors that are not believing them when they report problems. The only probIems noted in the original literature was constipation, so when people come in saying that they all of a sudden have crippling anxiety and their hair is falling out many doctors just blow them off. I know when I tried to tell one doc about some of the newer information she called me a conspiracy theorist. I'm sure there are quite few others that have had similar experiences. So at this point it seems that it is on patients to save other patients. We have known most of this info for close to two years now, so it's apparent advocacy groups and most medical proffesionals are just not going to talk about it. Hopefully this will change when the meds come out with black box warnings, which is something that Dr. Robbins told me he expects to see happen with these meds The CGRP monoclonal antibody drugs are an important option to have in our arsenal, but they pose a serious potential for harm if doctors are not aware of the side effects that can come up. And in all situations we need to be vigilant in our search for truth, even if we don't like it. Here is the article Dr. Robbins wrote. https://southernpainsociety.org/adverse-effects-and-clinical-trials-the-system-is-broken/ -Ricardo

....ok, starting to make sense...pain killer!....was probably going down the wrong road with vasodilation/constriction speculation. unlike opiates, could be n20 is hitting the right pain pathways irespective of blood vessels situation? perhaps weed similar... .....decades of this shit and "i'm still no bloody good at it" (to quote aussiebrian)...sticking around to learn, i wish more folks did...ya never know when the beast gonna morph and different weapons needed....

Yeah, cigs are horrible, they magnify the pain so much. weed doesn't help me much but it usually doesn't make it worse, sometimes maybe a little bit. O2 never worked for me but I never got it flowing enough. N2O is such a good temp pain killer that it has me wondering. Time to make some whipped cream. :p

Indomethacin users might be interested in this study that showed guarana to protect against lesions induced by Indomethacin. Guarana is a caffeine containing nut from South America and it is not hard to find. I would not be surprised if the caffeine actually made the Indomethacin more effective as well, but that's just a theory I have... https://pubmed.ncbi.nlm.nih.gov/14669256

@Bejeeber Admittedly, there have been very few clusterheads that have tried nitrous as an abortive so as far as working for other people we really don't know yet. But it works damn well for me

Hi, in India, the homeopaths mix up the medicine themselves. So dont know what it is. But since he's a friend, I will ask him.

Hi Vipul, would you be able to post the ingredients and their strengths (like 2x, 3x etc.) for the homeopathic meds you were given?

Jeebs, the Epi proved to be a provoker of Hell for me. Repeatedly! I cut my thumb with Machete cutting corn. It was sewed up no problem. But the 'hand specialist' was an idiot and it took 4 surgeries to fix the mess that he made. Anyhoo, I woke from surgery and was fine. No biggie actually. But, he pumped me full of epi. The hospital was 2 hours from home and they gave me no meds as it was supposed to stay numb for 4-12 hours post surgery. That was not true for me. It came alive in less than an hour and I had no pain meds and a lot of pain. I had 10 hits in the following 24 hours. My personal record. It was hell night. No cycle started though. It was summer and I was not in my normal cycle time just yet. The next trip to that place and they were told that it would be a general and NO epi ever again. I had no hits. When I had the great colonoscopy done, I told that one that I might need O2 post even though it was just sedation. She asked how I wanted it? 15LPM and a non-rebreather for 5 minutes and then 5 minutes at 5LPM. Well, they sedated me and I got a hit. So, they did full anesthesia at that point as I was thrashing allover according to them. I hit the recovery room, woke immediately and sat up - her cue on the O2! Cleared it right up and no more issue with that one. They were very shocked that I woke immediately. They had just told my husband that it would be over to an hour. Nope, she made a bat turn and let him know that I was up and almost ready to go. Now, when I go the THAT hospital, we have a procedure in place and my chart is noted for NO EPI. They also have O2 waiting when I wake. I can see the tank!! I made a believer out of that doctor. When the gallbladder came out, the O2 was right there for me. But, no epi, so no hit! I refuse to have dental work done during my 'normal' cycle months! My dentist won't work without epi. Yes, it shrinks the blood vessels to reduce the bleeding. It also provides better deadening of the area, so the dentist is happy with that and won't work without it. Were it possible, I would change dentists to get nitrous!! That would be the bomb!!!

Thank you for the cautionary tales @xBoss- that is some seriously messed up dentistry provoked hell. And @Ricardo, WOW, somehow I had missed or forgotten along the way the thing about laughing gas being an abortive???!!! I recall being given nitrous oxide as a grade school kid while getting some baby teeth molars removed, and man I was partying! I think it ended up being a serious inspiration for seeking out the party smokes when I could get access a couple years later.

Hey Ricardo! Are they wanting questions on how prescribed meds interact with MM and such? Questions on which meds are okay with MM and RC? I want to help, but am somewhat at a loss here. The only big one I know of off the bat is the licorice root protocol and MM. What is safe, if anything. Please, give me a bit more to go on. Thanks!