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Showing content with the highest reputation on 02/09/2021 in Posts

  1. ...hi Kat...can't speak to the effectiveness of amovig or it's effect on busting, but have been in clinical trials for another condition .. ....if you can work it around a busting schedule, or are willing to pause busting if need be, i would strongly encourage participation for the following reasons: ....#1...with a bullet...it might work! ...if it doesn't work, you have identified yourself as a potentially willing trial participant, for a defined condition, and they already have all of your pertinent personal data. recruiting for trials is a tedious, difficult, expensive undertaking....making participants a valued "commodity". once you are in the system, your chances for future opportunities goes way up. (added note, another one of the reasons i always encourage finding a HA specialist...they have knowledge of/access to trials...) ....Pebbles is absolutely correct...and the cost:benefit ratio may not work....but trials are ridiculously expensive and the sponsors motivation can be to your benefit...sometimes free, sometimes at reduced rate/couponed, sometimes you get access to meds that others don't (primary and adjuncts)... ....for the same reasons (trial sponsor cost/efforts/rewards in money and treatment successes) trial patients are treasured and (at least in my case) get boutique level care....with a care coordinator. means immediate access to docs and appointments and referrals and lab/procedure results and and and. careful, it might spoil ya to the regular assembly line..... ....trials are no guarantee of any better result than "standard of care"....that was the case for me. however, the information obtained is priceless to researchers/providers...finding out what doesn't work can be just as important as what does. the information obtained can be used to direct/redirect future efforts.....and the knowledge that you might be helping someone else down the line can be REALLY rewarding..... best jonathan
    3 points
  2. I gave it try a couple of years ago. I was well into a challenging cycle and gave it a 3 month trial. My cycle stopped for 18 months and when it reared its ugly head this past August I tried it again without any relief. After the Amovig I tried Emgality for three moths without any relief. In retrospect I belief the first Amovig trial corresponded witht eh end of my cluster cycle and it gave the illusion of success. I never had side effects from Amovig but emgality made me feel pretty crappy (flu like) for a day or two after injection. When you read the studies For this class of meds (a least Emality) they talk about reduction of frequency\intensity with 30% relief being the threshold. For me that's not worth the huge expense esp when other things have the potential to work better (D3, busting, o2, steroids, triptans) Every intervention has its ups and downs and often it seems like trying to hit a moving target. Sometimes the beast wins.
    1 point
  3. @Phantom99 im so hesitant when they say “it helps with migraines and possibly clusters too”. Clusters behave so differently and I’m always scared any disturbance from an unknown medication will make it worse. I don’t know. I would pass on it kat
    1 point
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