Jump to content

Latest D3 regimen details

Recommended Posts


Episodic sufferer here, have been since 2009 (although the beast gave me 7 years between my first and second cycle just as a massive tease). Normally have one cycle a year, lasting 4-6 weeks. Latest cycle has been tougher than usual.

There's obviously a lot of discussion about the d3 regimen and seems like the recommendations are somewhat fluid as new experiences and tweaks come to light. The official place to look on VitaminDWiki seems like it's potentially a bit out of date relative to what I've read here recently.

Just checking if there's a more up to date summary of the regimen available somewhere that I don't know about?



Link to post
Share on other sites

I follow the original that I started  several years ago year round as it keeps me cycle free. That would be the first picture in the Wiki paper. For me, 10.000 units per day it the right amount. It keeps me cycle free and my D3 is in line with the standards the doctor wants too. I add C, just because it is a good idea in winter. 

Perhaps Batch - XXX - will see this post and add info for you.


Link to post
Share on other sites

I think Quercetin might be, like verapamil, potentially contraindicated with the Candesartan drug I take. Seems like the advice is to be wary of Quercetin and any drugs that are changed by the liver?

The 3mg dose does seem high with that contraindication in mind.

That post from Batch also mentions turmeric and vitamin C, neither of which are directly mentioned in the official regimen advice. I guess the vitamin C comes from the multi vitamin, but turmeric seems like a distinct addition.

Link to post
Share on other sites

I have taken Benadryl for decades and just stopped last week. I have not noticed a difference at this point, but that is not to say that I won't have an issue when the allergies kick in again. 

They used to give it to kids for allergies and adults too, who took it for years. Now there is something new being stated about not for long term use. So, I am trying to delete for a bit. The only 'bad' news on it that I have found is if you have kidney cancer, don't take it, So, I am not sure whey the new 10 days only thing is out there. Sorry!!!

Link to post
Share on other sites

Hey Drewbie, All,

The basic regimen posted on vitaminDwiki is still valid for CH and MH.  I was in the process of updating it with results from the online survey when the COVID-19 pandemic hit the US in early February.  At that point I had two changes to supplements in the posted version.  The first is we've found the Bio-Tech D3-50 50,000 IU water soluble form of vitamin D3 to be faster acting with a higher bioequivalence in elevating 25(OH)D3 serum concentrations than the same dose of the oil-based liquid softgel vitamin D3 formulations.  I began suggesting this switch in 2019 here on this forum.  The same goes for the switch from the vitamin B 50/100 complex to the Methyl Folate + B complex as it also has a higher bioequivalence.   I began suggesting this switch from the vitamin B 50/100 complex to Methyl Folate + B Complex in December of 2019.

Vitamin C (Ascorbic Acid) and Turmeric (Curcumin) are also covered in the 2017 posted version of this regimen on vitaminDwiki.com.  I began posting about Quercetin some time in mid 2019 and if you attended the Clusterbusters Conference in Dallas in 2019, I briefed Quercetin as an addition to the basis regimen.  I also posted about Quercetin as a supplement in an immune boosting strategy to help prevent viral infections in early June of 2020.

The rational for the switch from Benadryl (Diphenhydramine HCL) to Quercetin was based on the capacity of Quercetin as an antihistamine.  As Diphenhydramine is an anticholinergic that easily leads to drowsiness and Quercetin has an excellent safety profile, the switch to Quercetin for CHers suspecting an allergic reaction makes good sense.

The emergence of the Wuhan virus and COVID-19 pandemic in early 2020 have posed additional considerations on the update to the posted version of this treatment protocol.  For example, I've always known a healthy immune system played an important role in helping to prevent CH and MH.  What I didn't fully grasp was the detrimental effects of a dysregulated immune system can be on CH.  The results of several studies of COVID-19 and treatments practiced by emergency medicine physicians in the Front Line COVID-19 Critical Care Alliance (FLCCC) focused on a dysregulated immune system as the primary threat to survival from COVID-19.  Their treatments include large doses of vitamin D3 (480,000 IU) on admission, Quercetin, zinc as well as IV vitamin C, and Thiamine (vitamin B1).   See attached.

I'm still working on the updated version of this treatment protocol.  That said the updating process is not a simple task.  Once I have a clean draft, it will go out to a select group of experts in nutritional science, nutritional medicine and headache specialists for chop and comments.  That will take at least a month or longer depending on the comments and suggested changes.   Until then, I'll keep you posted.

Take care,

V/R, Batch



  • Like 1
Link to post
Share on other sites

Thanks for the detailed responses everyone. I'm potentially coming to the end of my current cycle so won't likely be able to make a strong judgement on the efficacy of the regimen for me. However, I intend to start using the regimen anyway given there's obvious general health benefits to doing so.

Link to post
Share on other sites

Hey Drewbie,

Good move starting the anti-inflammatory regimen.  I've had my entire family and close friends taking it since 2011 and none of them have CH.  The first step is to see your doctor/PCP to discuss this regimen and to ask for lab tests of your serum 25(OH)D3, calcium and PTH.  Without these lab tests, CHers are shooting in the dark.  When you do get the results back, see where you stack up with respect to the studies in the following link.


Take care and please keep us posted.

V/R, batch


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

  • Create New...