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Hello im a new member here. I have been suffering from CH for over 10 years. Usually get CH in spring and fall that lasts for about a month. I usually stay away from any prescription meds due to their cost and because they just make next headache worse. Recently I had a bad flu that triggered nightly clusters. Since I had runny nose I started using nasal spray to clear out congestion. So one night I got up with a really bad CH and went to clear my nose and used over the counter nasal spray. Approximately 15 minutes later headache was gone and I quickly fell asleep. I never had any medicine act so fast against CH. I have been using nasal spray to fight CH for past 2 weeks and it worked everytime. Sparay that I use contains regular dose of Oxymetazoline. So Im just curious if this method worked for someone or maybe it will help you too if you havent tried it yet.

I've been using a generic oxymetazoline nasal spray for quite a while now with good results. It's best to use it as soon as the headache starts.

I have been researching oxymetazoline for some time now and have been using as a substitute for sumatriptan for nearly 3 years. I am 100% certain that this aborts my cluster headaches. Oxymetazoline as an α-adrenoceptor agonist, however it works as a full and potent agonist of serotonin receptor types 5-HT1A, 5-HT1B AND 5-HT1D, and is a partial agonist of 5-HT1C. Sumatriptan works as an agonist of serotonin receptor types 5-HT1B and 5-HT1D. It is believed that sumatriptan aborts cluster headaches because of cerebral vasoconstriction caused by its action as an agonist on serotonin receptor type 5-HT1D So I firmly believe oxymetazoline aborts cluster headaches. So far you are my first confirmation. Spread the word