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Hi Bigtime, welcome. It seems you did very well until know. I'm super happy for you and thanks for contributing your story here on the board. one thing I like asking you: This time, did the beast change in format? Same side, apearing exactly the same way as it did in the past or do you notice any change? thAnks

Some links I found. 35 year old woman with coronary artery disease has a heart attack after first dose of SQ sumatriptan. http://www.ncbi.nlm.nih.gov/pubmed/7783891 56-year-old female patient with migraine who experienced a myocardial infarction shortly after using sumatriptan, despite having had a normal cardiovascular evaluation. http://www.ncbi.nlm.nih.gov/pubmed/8682677 Risk of severe cardiovascular adverse events after the use of a triptan is estimated at 1:100,000 treated attacks http://www.ncbi.nlm.nih.gov/pubmed/20977405 42-year-old man with episodic cluster headache without history of coronary artery disease who was admitted to our coronary care unit for acute myocardial infarction after 3 h of subcutaneous injection of sumatriptan. http://www.ncbi.nlm.nih.gov/pubmed/16601942?dopt=Abstract If you keep looking there are more. Most cases, but not all involve people that already were experiencing some sort of heart condition. There are also a good amount of people reporting chest pain that turns out to most likely NOT involve any sort of heart problem. (There is something to also be said for the fact that just because you have not been diagnosed with a heart problem, that could still mean that you just have an UNDIAGNOSED heart problem) My take on everything I have read--if you have a pre-existing heart condition I would be pretty wary of taking sumatriptan. For the rest of us, be on the lookout for dangerous side effects but personally I am not too worried about it. There are a number of weird cases out there involving sumatriptan possibly having a negative cardiac event but with the unbelievably huge number of people that have at this point taken the drug with no problems, I'm not convinced it's something I should worry about enough to stop taking sumatriptan. I would however be very wary of mixing sumatriptan with certain meds (like verapamil). Anybody have any other cardiac info on sumatriptan, whether from research or anecdotal? -Ricardo

I want to expand on this to help CHrs make a better decision for themselves. The neurologist that I was seeing is on one of CH specialist list. He told me that the recommend dose is 2 per day but because clusters are so bad to inject every time I had one. He prescribed me Sumavel Dosepro 6 mg. Each injection cost $89. For 51 attacks that was $4539 in one week. It did give me cardiology problems for a couple of weeks. Not sure what the long term effects will be but sure I will have some. They know what the side effects are and do not care.