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Hey Spiny, I've kept my 25(OH)D serum concentration between 127 ng/mL and 188 ng/mL for the last 5 years and currently 163 ng/mL. In that time my serum calcium remained within its normal reference range so no hypercalcemia a.k.a., vitamin D3 intoxication/toxicity. My PCP is ok with my 25(OH)D this high as long as my serum calcium remains in the normal reference range. He still makes a notation in my medical record that he suggested a lower vitamin D3 dose. This is a CYA action. Accordingly, there's nothing wrong with a 25(OH)D serum concentration of 124 ng/mL as long as it keeps you CH pain free and your serum calcium remains within its normal reference range. Regarding the return of your CH after lowering the vitamin D3 dose. You just discovered the therapeutic dose that keeps you CH pain free. A couple days at a loading dose of 50,000 IU/day will get you back CH pain free a lot faster... Take care and please keep us posted V/R, Batch.

Hi Virr! I have been on the D3 Regimen for years now. Since 2011 or 2012, can't remember for sure. I have my D3 levels checked yearly. This year my number was 124 measured by US standards. This was higher than my normal 103. So, I decided to cut back on the D3 to 5,000/day instead of the 10,000/day I have been taking. Guess what? I have been slammed with O2 resistant hits. Normally I am nocturnal, but these were hitting day and night. So, upped my D3 again and took a dose pack of Prednisone. It has taken 6 days to get back on track mostly. I am not pain free yet, but I am getting there. Now, you might ask why I did this. Because the doctors stick with 100 as a top number here. Above is safe if your other tests are good. But, I listened to my old doc and sent myself straight to Hades. Never again unless something unforeseen steps up and messes with it! The medical profession needs to catch up and keep up. They do not and likely will not. You are your own best advocate. ATB