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@BoscoPiko actually, the primary substance contained in dried vitamin M is psilocybin which is what's known as the prodrug of psilocin......this conversion is normally achieved in the gut as stomach acid breaks down the shrooms.....once converted, the psilocin has the ability to cross the blood-brain barrier and moves out of the stomach and into the blood stream. I never took chemistry in school so I don't understand these processes well, but from what I've read, this conversion process is called dephosphorylation.....on the molecular level it amounts to removing one phosphor atom from the psilocybin molecule. When you dose using the lemon-tek method this conversion is accomplished by mixing dried, powdered M with lemon juice...so when you drink the lemon-tek mixture after soaking for 20 minutes, the psilocin can immediately transfer out of the stomach and into the blood vessels. As to the scope of the research, while the sub hallucinogenic doses may prove effective for some ailments, I believe clusterheads will require a larger dose to see any efficacy! DD

https://www.bnnbloomberg.ca/revolutionizing-chronic-cluster-headache-treatment-the-science-behind-lobe-sciences-1.1889147

It's always exciting to read of these new developments, however, this particular piece raises a lot of questions for me! Of the 5 major psychoactive substances in vitamin M, psilocin is the only one capable of crossing the blood-brain barrier and from every thing I've ever read, is very unstable after its conversion from psilocybin. DD

Thanks for posting this. I am always interested in new developments. Truthfully I was not aware that psilocin converted to psilocybin after breaching the blood brain- barrier. I do indeed need to research and learn much more! I suppose it was sad to read the focus of the study being partially geared toward children with severe anxiety... Since when did children suffer from anything other than how the next mud pie would turn out or if that rock you snuck into the middle of your snowball would inflict a proper sting on your brother's noggin effectively to worry about? I was happy to read the part about the sub-hallucinogenic levels in this study but at the same time conflicted with what I have researched on this site to be effective. Either way I appreciate you posting this. Cheers!

As I remember, Cindi, you are only taking verapamil, probably at a pretty low dose. So the hopeful part is that soon you'll have more of an arsenal. Don't know whether you have started the D3 regimen or tried any of the "Treatments Without Oxygen ..." that are mentioned toward the end of this document -- https://clusterbusters.org/forums/topic/6213-basic-non-busting-information/ -- which I'm pretty sure I would have linked to in your earlier thread. CH is very unpredictable for lots of people. With the pattern you have described here, I'm also wondering about triggers, which you can read more about here: https://clusterbusters.org/forums/topic/4568-triggers/ . (I'd suggest reading through the whole thread, not just the first post.)

Excited... been booking my journey today!