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@Bejeeberhi!! I actually do this technique all the time to help me with my tremor. If I find that my hands are particularly shaky, I do this for about 2 minutes until I reach a mild state of euphoria. It’s amazing what breathing can do

I find this routine to be effective at times (I asked ChatGPT to spell out the details and it supplied this): The technique involves inhaling through your nose for a count of 4, holding your breath for a count of 7, and then exhaling through your mouth for a count of 8. This is repeated for several rounds, usually four to eight times, depending on your comfort level. The idea behind this technique is that by slowing down your breathing and focusing on your breath, you can reduce anxiety and promote relaxation. It has been popularized by Dr. Andrew Weil, a well-known integrative medicine physician. It's worth noting that while many people find this technique helpful, it may not work for everyone. If you have any medical conditions or concerns about your breathing, it's always a good idea to consult with your healthcare provider before trying any new relaxation techniques.

I agree Denny. And why this way and not BOL-148? We made it in as an "orphan" disease only because they are restricting it to Chronics. If all Clusterheads are included, we are at about 250k - 300k total the last time I checked and that exceeds the 'orphan disease' restrictions. It holds the line at 200k. And the Orphan status 'grants seven-year market exclusivity to drugs that treat rare diseases.' So, getting that status gives them extra marketing power too. Why for kids? Yes, WHY! Money I suppose. Most do not take a recreational dose, they take what they need and it is pretty individual at that. I wish them the best and the best for every CHer. NOT just Chronics! So will Episodics have to fight the hard fight to get this script? On another note, this may show them that a Chronic needs a LOT of medicine while Episodics can usually get by with less. It may bite them in the end. So, add in the over-anxious kids to keep your funding coming perhaps? IDK.

Denny, is this because you just believe that a sub-hallucinogenic dose is just too little "medicine"? I guess my question here is just clarifying important semantics. To me, "sub-hallucinogenic" means that something might happen (or nothing might happen), but it's not a full-blown trip experience. So I'm asking whether you think a trip experience is essential, not for the trip itself but because that's the only way to get enough psilo? Or do you think a sub-hallucinogenic dose, with some effects, just not "hallucinations," could be okay? That's what Bob W is saying in the next paragraph, and Dr. Schindler actually uses the word "non-hallucinogenic" below to describe some successful busts. Here's Bob, from last year, saying that the the right dose is going to be sub-hallucinogenic: somewhere between no effects and a full-blown trip: "The small doses of psychedelics used to treat cluster headaches are usually enough to produce some felt effects, often described to me as a two-beer buzz. But these are still far less noticeable than the effects of a recreational dose." https://blog.petrieflom.law.harvard.edu/2022/04/18/small-doses-of-psychedelics-for-cluster-headaches/ This is Dr. Schindler [the person conducting the Yale research] reporting on the results of a 2015 CB survey of 496 people: "...infrequent and non-hallucinogenic doses were reported to be efficacious." https://pubmed.ncbi.nlm.nih.gov/26595349/ (To me, non-hallucinogenic and sub-hallucinogenic both mean the same thing -- no "trip.") More from Schindler (https://americanmigrainefoundation.org/resource-library/can-psilocybin-treat-cluster-headache/): "Researchers also discovered that for those who found the psilocybin treatments effective, the degree of symptom and pain relief was not directly related to the strength or intensity of the psychedelic experience. This indicates that “the mechanism [of cluster headache] is probably not directly related to the psychedelic experience itself,” says Dr. Schindler. “That’s in contrast to most studies in psychiatry [involving psilocybin], where the bigger your experience is on the test day, the greater your improvement weeks and months down the line.” Way back in 2006, from one of the Sewell/Halpern/Pope publications: "...given the apparent efficacy of subhallucinogenic doses, these drugs might benefit cluster headache by a mechanism unrelated to their psychoactive effects." https://www.semanticscholar.org/paper/Response-of-cluster-headache-to-psilocybin-and-LSD-Sewell-Halpern/e9aec20b22da4b258365f1e21d17ac3c62a48899