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Side effects from antibiotics in the quinolone class are often related to dose and duration. The most common concerning "side effect" is spontaneous tendon rupture particularly in older folks. This is relatively rare. Quinolones can also affect the metabolism of other medications. As a class they are relatively new on the medical scene. Cluster headaches have been along long before antibiotics so I would be very suspicious they have anything to do with cluster headache etiology. It would be more likely the condition the antibiotic is treating contributed to the attack rather than the treatment. Disease has been around much longer than treatments.

I don't think they're "intractable" unless they fail to respond to all conventional treatments, and I'm pretty sure that's not the case. It's possible that you won't have another cycle for a long time, or at all. More likely that you will, of course. Quite possible that the various CGRP meds will be better developed for CH by the next time you have a cycle, or another effective treatment will have been discovered/approved, and it will turn out to be easier for you than it has been for all the previous generations of people with CH. For a general overview of ways to treat CH, you might want to look at this file: https://clusterbusters.org/forums/topic/6213-basic-non-busting-information/ You'll probably forget most of what's in it, but if/when you do have another cycle, you'll know it's there. Asking myself if there's anything you should do now. I'd say to seriously consider starting some version of the vitamin D3 regimen (there's link in the post I linked you to above), so you are building up your D levels. As far as anyone knows, there aren't any bad side effects from following that regimen in a disciplined way. You don't say whether you received any prescriptions (maybe the diagnosis came after your cycle was over). You will read about triptans in the post above: they have their uses. Because the number of triptan devices (injectors or spray containers) that you can get at any time is limited, more than a few people fill their prescriptions for triptans when they are out of cycle so they have a "stockpile" when/if they need them. This is just something to consider. They're expensive. And you might never need them, or never really want to use them.