Tmac,
Seeing your doctor to obtain lab assays for your serum 25(OH)D3 calcium and PTH is prudent. As long as your serum calcium remains within its normal reference range and your PTH is in the mid to low normal range, there's no problem no matter how high your serum 25(OH)D3 assay. I get the same blurb from Quest on my 25(OH)D3 assays. I think it's computer generated.
It's obvious something is interfering with the vitamin D3 enabled genetic expression that helps prevent your CH. If it's allergy driven as I suspect, it could be there's so much histamine in your system, Quercetin is ineffective and even Benadryl (Diphenhydramine HCL) isn't all that effective either. Other sources of interference include anything that causes an immune system response like infections, (bacterial, viral or fungal), some Rx medications, trauma and surgery.
When are your CH occurring? If they're all at night while sleeping, try sleeping in a leather recliner in your family room. The rationale...
it could be dust mite poo. These little beasties have inhabited human bedding for thousands of years. They don't bite but their poo can be a potent allergen. Even if your wife wins the Good Housekeeping Seal of Approval, keeping sheets and bedding washed every other day may not be good enough, dust mite poo still gets into pillow and mattress stuffing.
Accordingly, to reduce exposure, try sleeping in a leather recliner for a couple nights. A recliner also has the advantage of keeping your head 8 inches above your heart. Even while sleeping, this will cause your heart to beat slightly faster to pump blood up to your brain. The extra work requires a little extra oxygen so your respiration rate will elevate slightly. This increases the arterial oxygen partial pressure and reduces your arterial CO2 partial pressure. Both these conditions help prevent CH. If your recliner has fabric upholstery, cover it with a plastic sheet. Dust mites colonize anywhere there are dried skin flakes.
If there's a reduction in CH frequency while sleeping in the recliner, it's time to invest in a Hypoallergenic and dust mite proof mattress cover and new pillows. Changing filters in the air handler of your heating and cooling system frequently can help cut down on airborne allergens in your home's interior.
If there's no joy with the recliner, your PCP/GP has several lab tests that should indicate weather or not you have an allergy. If the tests are positive, he should be able to get you a consult with an allergist.
Another way to find out if you're dealing with an allergic reaction is to ask your PCP for a short prednisone taper. If the pred taper is sufficient to drop your CH frequency, start looking for the cause. Hope this helps.
Take care and please keep us posted.
V/R, Batch