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My pharmacist called topirimate the "California drug" cause it makes you skinny and stupid. It did help to reduce my frequency, but ended up with a kidney stone and after testing it was the kind related to taking topirimate, went off it and my entire existence exploded, 5-who knows many hits a day, days on end awake because it will not let me sleep. Others have had the same experience coming off it as well, I hope that will not be the case if and when you go off it. Seems my triptan experience is also not alone, was doing injections and for a while, I could abort every shot, then one day one did not have the intended effect, then more often to nearly 50/50 shot if it would work or worse and the price....bec ame untenable to pay that much to work less and less