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Hi all, A pretty unusual post this! In the last six months, I've had some testing periods with CH. These experiences lead me to write a couple of songs inspired by what I've gone through. I figured it would be cathartic to share the recordings (only rough demo tracks!) with the community here. It got me wondering whether anyone knows of any professional/famous artists who have ever released songs inspired by CH?! Anyway, here are links to the two songs. I hope there's something there you can associate with - if not, that will say a lot about my song writing skills Until The Next Time - https://soundcloud.app.goo.gl/fqGAE Two Sides - https://bit.ly/3hupDYB Best wishes to you all, Drewbie

.....a full but DUSTY O2 tank being among the most beautiful sights ever.. I liked to keep one around.....ya never know...

Well, I was going to respond yesterday morning, but had become busy and had to put it off, but I'm glad I did because after about 5 days of being mostly pain and shadow free, I was smacked with a kip 8 for about 2 hours with a terrible 2 to 3 level linger till I fell asleep. However, I want to mostly attribute that to a possible slapback after a wonderful bust the previous night....and I bumped the B1 back up to 750mg, just in case. Now, after thinking back, I would have to say that yes CHFather, because right after that big post on the 22nd, they came back at about one attack each evening. I think it was slow-going because I cautiously increased the B1 dosage, and was mostly getting hit every evening still with kip5's to 7's, and one at work which really sucked. Trying to enter patient's data while quietly fighting off a kip4 for about 3 hours with no shots or and relief, was an awful challenge. But, once I reached 750mgs (which I think was on 6/25) I still got them every evening, BUT, they decreased very slightly in intensity and duration each night until the last mild kip 4 on 7/4. But my head had been noticeably clear and even shadow free (aside from hotdog experiment) until last night. I feel the B1 and mm are working hand in hand, and once I get my D3 serum to optimal levels, I think I will have finally reach busting nirvana. lol Now, I kinda feel like a jerk, because I am going to have to call the O2 service people to go ahead and deliver the tank, because I got to cocky and told them to hold off last week. I have great benefits through the hospital now, but still cant seem to get a smaller travel tank. So, I will prolly have to go the welders tank route for that one. I hope this all helps and fills in any blanks. PF wishes!

Brad, very glad to read this! I'd like to consider adding B1 to our list of possibly-beneficial treatments, but I have a question. You first reported using the B1 on June 22, and it seems you started the B1 on 6/21. In your most recent post, you say that you had bad attacks up to July 4 (~13 days). In the case study you referred to, the patient had "decreasing frequency of attacks until they disappeared completely within 10 days." Was your experience like this, with steadily decreasing something (frequency or severity)? Sounds more like in your case it was more like same same same over. If you credit the B1 in part for ending your cycle, is that maybe because you ramped up your dosage slowly? (I would suggest that during your PF time (may it last forever, but just in case) you might want to work on getting an O2 system.) Glad you can go back to the job you worked so hard to earn, and keep up your studies toward that next one!

The company is "...doing a lot of preclinical work to complete a package for an IND filing for sometime in the fall, for the full-blown phase two clinical trials for BOL-148.” They have acquired a patent to make BOL without having to use LSD to make it. That's a big deal. https://www.forbes.com/sites/amandasiebert/2021/01/18/betterlife-pharma-is-developing-second-generation-psychedelics-drugs-that-leave-out-the-trip/?sh=1405582f648f&fbclid=IwAR1qjwmeOl-LLa9KQyetBMeRSQpBtwKJmmpz0xxX27kFM6-1cRHmE-T5e0o

Excellent elucidation of this BOL spectacle and all the nutty baloney surrounding it CHfather, thank you.

Agreed -- it's stunningly wrong. (I should mention that the BOL trial was funded by ClusterBusters.) Many of us here (or several of us, at least) have observed or participated in many experiences of trying to make BOL available over the past ten-plus years. A company, Entheogen, was founded in part for that purpose. But Entheogen couldn't raise enough money to do the necessary clinical trials toward FDA approval. Clinical trials are very expensive, and among other things potential investors didn't see the potential market as big enough to justify the investment -- not to mention that at least at that time, there was a real concern that an LSD-based substance could not get approved no matter what the trials said. (The trial funded by CB didn't meet any of the criteria for rigorous clinical testing.) There were patents to be dealt with, not just the patent for BOL itself but also a patent that was taken out for using BOL to treat CH. That patent created a pretty ugly rift between two doctors who were very big supporters of CB and pioneers and the use of psychedelics to treat CH. (Money changes everything, as they say.) As the article notes, a big deal now is the ability to make BOL without starting with LSD. So, prayerfully, things are better now in many ways. One of those ways, which is a double-edged sword, is the potential for BOL to serve a much bigger market than the CH community. If it has potential as a treatment for depression, for example, there will be much more interest in making the investment--but the clinical trials will probably focus on that, and possibly mean that BOL would be available, but its use for CH would be "off-label" in the sense that it wasn't demonstrated by clinical trials. If you're a drug manufacturer, you have an additional issue related to CH. If doctors don't diagnose CH correctly, they won't know that their patient will benefit from BOL. And even if they do diagnose CH correctly, we have seen that way too many doctors don't even prescribe oxygen, or don't correctly prescribe practically anything. In part, they don't prescribe O2 because they have no familiarity with high-flow O2 with their patients, so they are reluctant/afraid to prescribe it. It might be tough to get them to prescribe something LSD-based. (And I remember reading somewhere that most doctors believe that they are very effective at prescribing for CH. Probably because their patients don't come back, or don't know any better.) So you have a massive education campaign to do to (1) get CH diagnosed properly, and then (2) get BOL prescribed. The cost of that is part of the cost-benefit analysis that goes into pharma companies' analysis of getting into a clinical trial. I guess I'm saying all this because there are many reasons now to be more optimistic than ever, but, as Jeebs said up above, we've been through a "maddening (and then some) history of false starts," so I am trying to temper my optimism.

I agree with @Chris Moore. Surely there's something the CH community can do to help things like this on their way? I just find it completely staggering that, despite the obvious potential of BOL-148, that here we are over 10 years after a successful study, this option remains elusive as a treatment. I find it so damn demoralising that options exist to potentially change lives and yet those things don't reach patients at all, or at least not in legal ways. It's kind of abhorrent, for example, that CH sufferers who benefit from psychedelics have to break the law - a face considerable jail time - in order to do so. It just seems inhumane that governments and the medical community aren't able to make pragmatic decisions in the interests of reducing suffering. There just seems to be a whole lot of hypocrisy where it comes to pharmaceuticals. So many legal prescription drugs that are capable of far greater harm than currently illegal therapeutics. It just makes me feel depressed that we've not been able to move forward as a human race to make more pragmatic decisions. I just really hope we're on the verge of change this time around. It's just appalling that people have to suffer great pain when there really might be a solution already out there. It's just wrong.

Whoa - wouldn't that be incredible if someone was actually able to get BOL-148 fully approved, manufactured and available for prescription? For that matter over the counter availability would be fine with me . To see this non-hallucinogenic version of LSD, reputedly much more effective for CH, finally become available could be such a game changer, and such a longer than lonnnnnng time coming after it it's promise has been known for so many years, with the maddening (and then some) history of false starts.