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"....with BOL-148 we have to conduct an ascending dose Phase I trial, which we’ll be starting next quarter. We plan to share top line data from the study in the first quarter of next year, and then we’ll move straight onto Phase II..." So highly appreciative that this is occurring, while also remaining exceptionally jaded (after so many false starts and disappointments) regarding the question of whether we will ever get our hands on this non hallucinogenic super LSD / super busting substance that has clinical trials dating back to the 1950's.

Interesting article from May. Talks about Cluster and Migraine https://psych.global/ceruvia-lifesciences-on-lsd-and-bol-148/

I see what you did there combining hitch hiking and Atlantic crossing into one image. This thread is becoming so bloody brilliant, medals should be bestowed for it, if we don't get kicked the feck off of here first.

It's pretty darn interesting makes me think about micro dosing just for health purposes.. And yea I'm not a huge fan of the interviewer but Paul is a pretty cool dude..

Yes, thanks Vipul. Issues requiring hip surgery are commonly the only extended use pred side effect mentioned, but, from https://creakyjoints.org/living-with-arthritis/coronavirus/treatments/prednisone-steroids-immunosuppressing-coronavirus/: Corticosteroids like prednisone have a laundry list of potential side effects, including high blood pressure; high blood sugar; glaucoma; issues with sleep, mood, and memory; weight gain; fluid retention and swelling; osteoporosis; and more. Side effects tend to increase with higher doses and longer duration of use. Another common side effect of corticosteroids like prednisone is increased risk of infections, including bacterial, fungal, and viral infections. This is particularly important to understand right now in light of the current COVID-19 crisis. A May 2020 editorial in the Journal of Clinical Endocrinology & Metabolism cautioned that people who regularly take oral steroids should be considered higher risk for COVID-19 and may be more prone to developing complications.

Thank you for the update, Vipul.

Some scientists are working to develop molecules based on psychedelics that provide the therapeutic benefits of the drugs but without the hallucinations God I hope not only joking would be an amazing thing if they can

Hi, been looking over the net and there are many articles suggesting cataract formation as a side effect of heavy usage of Prednisone besides many others. And to be honest, I did overuse them.