Pebblesthecorgi

Seems like a novel idea. Not really sure what the basis would be. One study showed maybe help in migraines. Looks like there is one study recruiting https://clinicaltrials.gov/ct2/show/NCT00184587 Seems like a reach

Not helpful. The principles of craniosacral therapy are sound and have a role. Such adjustments may mitigate parts of the cycle a bit but like other forms of physical medicine the treatment is fleeting and not sustained. Balancing your diaphragms is good for wellness and overall health but our beast is a bitch. (in a gender neutral sort of way)

I had a chance to read through the online info at clinical trials. Any study like this is a lot of work because of the neuro ratio protections and generally inane people who serve on institutional review boards. As a starting point to collect data regarding safety of Vitamin D and the other factors it will be helpful. I am a bit skeptical that the time frame is adequate or that the studied will be powered enough to see the predicted outcome. More importantly because the evolution of the “Batch Protocol” has been ever tweaking what is being studied is certainly a stripped down version which may give a false negative. These things are so much work and only admiration can be extended to the instigator\/innovator for persistence and dedication. One last thought. Because the D3 dosing is fairly high from a conventional perspective it would be beneficial to find some pharmacologist looking to create safety data for high dose D3 much like has been done for psilocybin. But that’s another kettle of fish.

Weather seems like it is a factor and in the throws of a cycle we reach for any explanation for our pain. With barometric pressure reports on our phones, watching the weather patterns etc. We all desperately look for an explanation so we can find hope in certain patterns. I used to think it was barometric pressure drop, then I thought it was barometric pressure instability, for a while I was convinced moon phase mattered. I have tracked for myself and in my case weather changes are coincidental to whatever circadian trigger hits our hypothalamus. I believe there are migraine tracking apps looking at weather too. Most studies debunk pressure changes but some suggest validity. There are lists of places with the least to most barometric pressure changes and I do not think it correlates with incidence of disease.

Congratulations. This is the sort of stuff that puts wood in a pencil. Greatly looking forward to see how enrollment goes given the pace of filling spots in the psilocybin study. I give you all my respect for your hard work. Your success criteria is a pretty high bar given the accented success of CGRP meds. Exciting

I believe imigran is sumatriptan which is Imitrex in the US. There have been sporadic shortages of the drug (likely created shortages to push newer CGRP meds (me being cynical)). I'd look for generic sumatriptan

I don't believe the shot itself can trigger. If you want to be extra cautious ask for one without Thimerosal (an antibacterial preservative). Flu shots typically are administrated this time of year and for many cluster heads the equinox proved challenging. Then again maybe its my imagination. Do whatever you can to stay safe and flu free. The next wave is a coming and staying away from health care facilities is always a good idea.

I would continue to caution and emphasize nuanced differences. Do not let desperation be your guide. There is much confusion regarding psychedelic treatments and expectations. When it comes to psychiatric conditions like PTSD, treatment resistant anxiety, treatment resistant depression and end of life trauma psychedelics act like a conduit to facilitate active therapy. To achieve maximal benefit the psychedelic therapy should incorporate preparation, a psychedelic experience in proper set and setting with a knowledgeable guide/therapist and meaningful integration. This can take many forms and most societies have appropriate folks to serve these roles. Cluster headaches are a bit different. intervention with the psychedelic may actually be therapeutic without all the other support. Sure being properly prepared and tuned in makes the experience positive and certainly the "afterglow" helps deal with some of the life altering effects clusters cause but psychedelics seem to have robust effects in many to space out or stop cluster cycles. We still need better evidence this really works but it sure seems to have promise. So taking ketamine by itself even if the administrator has skills solely related to safe administration has the potential to be effective for cluster headache relief. If you want it for anxiety or PTSD adjunctive therapy is important. If you do pursue seeing a person qualified to administer ketamine therapy be sure to ask them to include some decadron (steroid) and have the high flow O2 available.

@Snowflake Lots of stuff going on my friend. Stay strong and determined. Life is a gift and even if you have to eat shit a lot the times in between offer you an opportunity to make the world a better place. Regarding suicidal ideation. This is very common for clusterheads. We all know its is true and survey data and personal stories all support the disproportional number of folks who choose to exit this earth and reenter the cosmic stream. The option of suicide can be empowering because you have the control NOT To Do It. Its good to have options and no one can take that away. It is much better to deny the beast the pleasure of self destruction and seek ways to improve the world. That way everyone wins. Ketamine has remarkable potential to help break a cycle of suicidal ideation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380583/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356805/ https://www.psychiatrictimes.com/view/does-ketamine-hold-promise-mitigating-suicide-risk http://scivisionpub.com/pdfs/titrated-serial-ketamine-infusions-stop-outpatient-suicidality-and-avert-er-visits-and-hospitalizations-918.pdf Now pay attention, this is important: The efficacy of ketamine and other classic psychedelics is in the context of knowledgeable directed therapy. These approaches need to be supervised by someone with familiarity and mental health training. The drugs put one in a state of mind to do the difficult work of therapy and get favorable long term results. Sure there are folks who believe they can do it alone, don't need help, the drug itself will get you what you need. This is patently false and dangerous when done by someone who is in mental distress of has an underlying psychological problem. Psychedelics in a mentally healthy person can be a great tool of self exploration but an unstable soul can get in real trouble with self directed trouble. There is an enormous upside to using psychedelics to treat a variety of recalcitrant mental health conditions but individually guided therapy is a recipe for a bad headline. Be strong, stay strong, figure out how to get what you need. Knowledge is empowering

Suicidal ideation is serious stuff. There is very strong evidence that therapy with ketamine will knock out the harmful thoughts and allow therapy to progress positively. I personally believe it would be a harmful idea to attempt to manage your situation using psychedelics without knowledgeable support. Depending where you live there are an emerging number of practioners who know how to use these medications effectively. Please seek appropriate support. This is a study now enrolling again that you might consider. https://clinicaltrials.gov/ct2/show/NCT03866174 Also there is a multicentered study going on sponsored by MAPS. When conventional treatments fail its is worth looking at some of the sanctioned research. T

Suicidal ideation is serious stuff. There is very strong evidence that therapy with ketamine will knock out the harmful thoughts and allow therapy to progress positively. I personally believe it would be a harmful idea to attempt to manage your situation using psychedelics without knowledgeable support. Depending where you live there are an emerging number of practioners who know how to use these medications effectively. Please seek appropriate support.

yup it sucks to be dependent on such harshness to survive. Similar to needing high dose steroids when the equinox's and solstice's come around. Stay strong friend

Most of the info you will get here regards Cluster headaches. Cluster headaches are not migraine headaches. There is some treatment overlap with triptans and CGRP meds but the mechanism of attack and treatment response are different. Oxygen therapy does not really help migraines. MM have had disappointing results for migraines as well. The effect of MM on spirituality, coping and managing chronic conditions transcend many conditions. That alone is a benefit many appreciate. D3 protocols seem to have positive effects for migraines according to info Batch has posted.

I do a search every once in a while to locate stock. Never any luck through "research chemical" channels. It is unfortunate since its not much of a psychedelic and I personally though it was very effective in helping with cluster attacks. I know some folks had a large stock, I wonder if they are still using on a scheduled basis

A familiar story. I have tinnitus on the cluster side. In most cases its related to a loss of hearing. I would have an ENT and/or audiologist look you over. It might be something simple like wax or something else treatable. The ringing sucks and learning to calm your inner self (like meditation) can help. I would not automatically attribute it to the clusters. The flat affect, dull senses, shadows and sluggishness are classic post cycle stuff Some is the sleep deprivation but I suspicion nervous system fatigue contributes.

I'm not versed personally in that material but from all I have read 50-100 mcg is the most common dosing in the recreational crowd. The material itself is very safe from a phisiological perspective so some use larger doses but I believe there are diminishing returns beyond 200 mcg. The data I have reviewed regarding microdosing reports using 10% of a recreational dose spaced out 4-7 days. So 10 -20 mcg would be the established "microdose". From what I gather folks dilute the material in a dropper style bottle and administer it under the tongue. Obviously a trusted source is required which is the biggest obstacle. The sponsor of the study (Beckley Foundation) is a powerhouse of research funding and support worldwide for sensible psychedelic research and use. They pair closely with MAPS on a lot of things but are independent. A wealthy heiress provides the base funds.

https://journals.sagepub.com/doi/full/10.1177/0269881120940937 I hope this brings you the full text. The file is too large to upload

Does he/she give a reason why? Makes no sense if your doctor can read. Either ignorant or an insurance company shill. Ask them to look up cluster headache treatment options on Up-To-Date. If he/she is not familiar get another doc. Any physician can do it if they have a license.

I am happy you are improving. As regards supplements and the fight against viruses (covid) I urge caution. Most of the info we have on things like vitamin C, zinc quercetin, and other supplements is confusing and incomplete. There is certainly no harm in using these strategies as suggested but please do not treat them as a protective shield and please practice social distancing and masking as appropriate. The pendulum of what works and what does not is swinging fast regarding covid and other viral infections. Knowledge is being transmitted faster than it is being vetted. Do everything possible to avoid getting infection and don't treat anything as though you are immune or impenetrable. Heck even if you have had a virus you can get it again in some instances. I don't wish this to turn into a covid discussion but caution is advised/needed.

I don't think you will get an answer to this because of the variety of herbal products out there. My observation from attending CB conferences is that a significant number of clusterheads are smokers. I have heard neurologist state this is a cause of the clusters but I suspicion the opposite is true. Nicotine is a vasoconstrictor and vaso constriction is desirable in aborting cluster headaches. So if you have a headache and smoking helps even a little you are reinforced to smoke. It becomes a vicious cycle. There are plenty of cluster heads who do not smoke so drawing conclusions is hard even with a more common use on inhalant. Pretty much anything you inhale into your lungs isn't good for them. The smoke/vapor causes irritation and allows other problems to manifest.

You have been given some significant challenges. Your strength should be an asset as you control the conditions. Personally if you have had busting success in the past I would try busting while using your current Stills meds. If you are stable on the meds and they are effective don’t start making your body confused by changing the dosing.. Prednisone has been identified as a blocker by some but there is little understanding why it would block. Ten mg is a relatively small dose. If you don’t get results you might briefly lower the steroids but my guess is you will be fine. My experience was taking 100 mg prednisone a day did not stop the effects of mm and when the mm effect kicked it I was able to get off the steroids. That too is anecdotal so take it for what it’s worth. the methotrexate is an anti metabolite metabolized in the gut and liver. It doesn’t use the same breakdown enzymes as psilocybin so it should be ok. As you are aware methotrexate and chronic steroid use a necessary serious treatment in these types of rheumatologic conditions so vigilant monitoring is critical. Stay strong

Side effects from antibiotics in the quinolone class are often related to dose and duration. The most common concerning "side effect" is spontaneous tendon rupture particularly in older folks. This is relatively rare. Quinolones can also affect the metabolism of other medications. As a class they are relatively new on the medical scene. Cluster headaches have been along long before antibiotics so I would be very suspicious they have anything to do with cluster headache etiology. It would be more likely the condition the antibiotic is treating contributed to the attack rather than the treatment. Disease has been around much longer than treatments.

My understanding that this is largely painless and completely sleep related. It is classified as a sleep disorder

It is an analogue of ketamine. As with everything new and especially off label, there are many variables and there is really know way to know. Getting it and having enough would be pretty significant hurdles. The packaging wants the person to be on an antidepressant as well. I think it would be hard to find a willing prescriber and an insurance company willing to go along

Good luck